Evidence map›Paper›PMID 39755701›Full record

ArticleScientific reports2025

Synthesis, biological evaluations, and in silico assessments of phenylamino quinazolinones as tyrosinase inhibitors.

Sara Moghadam Farid, Shahram Moradi Dehaghi, Aida Iraji, Mohammad Mahdavi, Mina Saeedi

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Enzymatic, cell-based, andRSC advances · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara Moghadam FaridDepartment of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran.
Shahram Moradi DehaghiDepartment of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran.
Aida IrajiDepartment of Persian Medicine, Research Center for Traditional Medicine and History of Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. iraji@sums.ac.ir.
Mohammad MahdaviDepartment of Persian Medicine, Research Center for Traditional Medicine and History of Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. momahdavi@sina.tums.ac.ir.
Mina SaeediMedicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Funding

Vice-Chancellor for Research, Shiraz University of Medical Sciences 30936
6 · The paper itself

Abstract

A series of novel phenylamino quinazolinone derivatives were designed and synthesized as potential tyrosinase inhibitors. Among these compounds, 9r emerged as the most potent derivative, exhibiting IC

Indexed as

Enzyme InhibitorsMolecular Docking SimulationMolecular Dynamics SimulationMonophenol MonooxygenaseQuinazolinonesAntioxidantsCatalytic DomainKineticsStructure-Activity RelationshipAntioxidantsEnzyme InhibitorsMonophenol MonooxygenaseQuinazolinonesDFTMolecular dynamics simulationPhenylamino quinazolinoneTyrosinase

Identifiers

PMID39755701
PMCPMC11700089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.