ArticleBrain stimulation
MRI free targeting of deep brain structures based on facial landmarks.
Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07361328 (Low-intensity Ultrasonic Neuromodulation for Alleviation of Fibromyalgia Symptoms), which is not on this map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Low-intensity Ultrasonic Neuromodulation for Alleviation of Fibromyalgia Symptoms
Who cites it
2 citing papers in PubMed.
- Reducing Cranial Morphology Error in F3 Scalp Localization: Comparison of Heuristic and Regression-Based Methods.Brain and behavior · 2026Article
- Role of thalamus in human conscious perception revealed by low-intensity focused ultrasound neuromodulation.Nature communications · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Emerging neurostimulation methods aim to selectively modulate deep brain structures. Guiding these therapies has presented a substantial challenge, since imaging modalities such as MRI limit the spectrum of beneficiaries. In this study, we assess the guidance accuracy of a neuronavigation method that does not require taking MRI scans. The method is based on clearly identifiable anatomical landmarks of each subject's face. We compared this technique to the ideal case, MRI-based nonlinear brain registration, and evaluated the accuracy of both methods across ten targets located in deep brain structures: 7 targets in the anterior cingulate cortex as well as the anterior commissure and posterior commissure. Compared with the ideal case, the average localization error of the MRI-free method was 5.75 ± 2.98 mm (mean ± sd). These findings suggest that this method may provide sufficient compromise between practicality and the accuracy of targeting deep brain structures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.