Evidence map›Paper›PMID 39754711›Full record

ArticleCancer communications (London, England)2025

Parkin deficiency promotes colorectal tumorigenesis and progression through RIPK3-dependent necroptotic inflammation.

Zheming Wu, Huaping Xiao, Jake A Kloeber, Yaobin Ouyang, Ping Yin, Jinzhou Huang, Bin Chen, Shouhai Zhu, Jing Lu, Yiqun Han and 6 more

Abstract read
In one paragraph

Article in Cancer communications (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zheming WuDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Huaping XiaoDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Jake A KloeberDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Yaobin OuyangDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Ping YinDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Jinzhou HuangDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Bin ChenDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Shouhai ZhuDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Jing LuDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.
Yiqun HanDepartment of Radiation Oncology, Mayo Clinic, Rochester, USA.
Xinyi TuDepartment of Radiation Oncology, Mayo Clinic, Rochester, USA.
Sonja DragojevicDepartment of Radiation Oncology, Mayo Clinic, Rochester, USA.
Kuntian LuoDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.ORCID https://orcid.org/0000-0003-1938-3091
Adrian T TingDepartment of Immunology, Mayo Clinic, Rochester, USA.
Meng WelliverDepartment of Radiation Oncology, Mayo Clinic, Rochester, USA.
Zhenkun LouDivision of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, USA.

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI AKHILESH PANDEY · 1985 to 2026
$151.3M
Medical Scientist Traning Program at Mayo ClinicT32GM065841 · NIGMS · MAYO CLINIC ROCHESTER · PI KAUFMANN, SCOTT H, SCHIMMENTI, LISA A · 2003 to 2022
$5.8M
Regulation of Necroptosis and inflammationR01CA224921 · NCI · MAYO CLINIC ROCHESTER · PI LOU, ZHENKUN · 2019 to 2023
$1.8M
NCI NIH HHS P30 CA015083NCI NIH HHS R01 CA224921NIGMS NIH HHS T32 GM065841NIGMS NIH HHS T32GM65841NIH HHS R01CA224921
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39754711
PMCPMC11999878

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.