Evidence map›Paper›PMID 39754651›Full record

ArticlePediatric radiology2025

Cerebellar hemorrhage in neonates: pattern analysis by ultrasonography and magnetic resonance imaging.

Gayoung Choi, Young Hun Choi, Seul Bi Lee, Yeon Jin Cho, Seunghyun Lee, Jung-Eun Cheon, Seung Han Shin, Bo-Kyung Je

Abstract read
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Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Gayoung ChoiDepartment of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Republic of Korea.ORCID 0000-0002-2004-5228
Young Hun ChoiDepartment of Radiology, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101, Daehak-Ro, Jongno-Gu, Seoul, 03080, Republic of Korea. iater@snu.ac.kr.ORCID 0000-0002-1842-9062
Seul Bi LeeDepartment of Radiology, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101, Daehak-Ro, Jongno-Gu, Seoul, 03080, Republic of Korea.ORCID 0000-0002-5163-3911
Yeon Jin ChoDepartment of Radiology, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101, Daehak-Ro, Jongno-Gu, Seoul, 03080, Republic of Korea.ORCID 0000-0001-9820-3030
Seunghyun LeeDepartment of Radiology, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101, Daehak-Ro, Jongno-Gu, Seoul, 03080, Republic of Korea.ORCID 0000-0003-1858-0640
Jung-Eun CheonDepartment of Radiology, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101, Daehak-Ro, Jongno-Gu, Seoul, 03080, Republic of Korea.ORCID 0000-0003-1479-2064
Seung Han ShinDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-7008-4073
Bo-Kyung JeDepartment of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Republic of Korea.ORCID 0000-0001-8335-9980

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebellar hemorrhage in neonates is increasingly being identified but is still underdiagnosed. While magnetic resonance imaging (MRI) is the optimal imaging modality for cerebellar hemorrhage evaluation, ultrasonography (US) is commonly used for screening. Characterizing the patterns and distribution of cerebellar hemorrhage lesions can help facilitate its detection by aiding to focus on prevailing type of cerebellar hemorrhage.

objectiveThis study aimed to analyze the patterns of cerebellar hemorrhage in neonates, comparing US findings with MRI. MATERIALS AND

methodsThis was a retrospective study of 765 neonatal intensive care unit (NICU)-admitted neonates who underwent brain MRI due to various clinical and radiological requirements. Two pediatric radiologists reviewed brain MRI and US in consensus, and cerebellar hemorrhage patterns were classified based on MRI findings: type 1, punctate cerebellar hemorrhage without cerebellar volume loss; type 2, focal cerebellar hemorrhage with cerebellar volume loss; type 3, ovoid/crescent cerebellar hemorrhage in the periphery of the cerebellar hemisphere; type 4, isolated vermian cerebellar hemorrhage; type 5, cerebellar hemorrhage involving almost the entire cerebellar hemisphere. The distribution and US detection rates of cerebellar hemorrhage were compared according to the cerebellar hemorrhage type.

resultsA total of 56 (33 male, 23 female) cases (7.32%) among 765 MRIs showed cerebellar hemorrhage (median gestational age, 27 + 1 weeks [IQR 5 + 2]; median birth weight, 955 g [IQR 882.5]). The most common pattern was type 1 (60.7%). Type 3 cerebellar hemorrhage was more commonly observed in the inferior and peripheral cerebellum compared to types 1 and 2 cerebellar hemorrhage (P=0.002). In retrospective review of images, type 3 was the most commonly missed type of cerebellar hemorrhage (initial US detection rate, 33.3%; retrospective US detection rate, 75%).

conclusionThis study underscores the importance of understanding cerebellar hemorrhage patterns and suggests that careful inspection of inferior and periphery of the cerebellum is important to avoid missed diagnosis of cerebellar hemorrhage.

Indexed as

Cerebellar DiseasesCerebral HemorrhageIntracranial HemorrhagesMagnetic Resonance ImagingCerebellumFemaleHumansInfant, NewbornMaleRetrospective StudiesUltrasonographyCerebellar hemorrhageCerebellumInfantMagnetic resonance imagingNewbornUltrasonography

Identifiers

PMID39754651
PMCPMC11805865

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.