Evidence map›Paper›PMID 39754487›Full record

ArticleClinical nursing research2025

Atherosclerotic Cardiovascular Disease Risk Scores are Associated with Carotid Intima-Media Thickness.

Emily K Mewborn, Elizabeth A Tolley, David B Wright, Amy L Doneen, Ansley G Stanfill

Abstract read
In one paragraph

Article in Clinical nursing research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emily K MewbornSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-7830-8756
Elizabeth A TolleyCollege of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
David B WrightPremier Prevention, Memphis, TN, USA.
Amy L DoneenThe Prevention Center for Heart & Brain Health, Spokane, WA, USA.
Ansley G StanfillCollege of Nursing, University of Tennessee Health Science Center, Memphis, TN, USA.

Funding

Targeting Research and Academic Training of Nurses in GenomicsT32NR009759 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CONLEY, YVETTE P · 2006 to 2025
$4.5M
NINR NIH HHS T32 NR009759
6 · The paper itself

Abstract

Atherosclerotic cardiovascular disease (ASCVD) risk calculators estimate the 10-year incident risk of myocardial infarction (MI), coronary artery disease (CAD) death, or stroke; however, they lack comprehensiveness and accuracy. Carotid intima-media thickness (CIMT) is a surrogate marker that may improve risk estimation acumen. The objective of this study was to derive ASCVD risk scores from historical data and determine whether these risk scores are associated with the history of subclinical CAD and CIMT. This retrospective cross-sectional study used an existing dataset of individuals with prediabetes. Subclinical CAD history was defined as the history of CAD, coronary plaque, or coronary revascularization without a history of MI. The online ASCVD Risk Estimator Plus calculator was used to derive individual risk scores. Chi-square or Fisher's exact tests for categorical variables and ANOVA for continuous variables detected differences among ASCVD risk categories. Linear regression of CIMT measurements on ASCVD risk scores ascertained ASCVD risk scores' utility in predicting CIMT measurements. The sample included 86 participants, 28% with a history of CAD, 60% male, and 95% White. No differences in risk scores existed between participants with or without CAD. Individuals with higher ASCVD risk scores were older (

Indexed as

AtherosclerosisCarotid Intima-Media ThicknessCoronary Artery DiseaseAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk Factorsatherosclerosiscarotid intima-media thicknesscoronary artery diseaserisk estimation

Identifiers

PMID39754487
PMCPMC12052478

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.