Evidence map›Paper›PMID 39754218›Full record

ArticleEuropean journal of medical research2025

Liquid biopsy in organ damage: introduction of an innovative tool for assessing the complexity of blunt splenic injury.

Aliona Wöhler, Bingduo Wang, Robert Schwab, Veronika Lukacs-Kornek, Arnulf G Willms, Miroslaw T Kornek

Abstract read
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aliona WöhlerDepartment of General, Visceral and Thoracic Surgery, German Armed Forces Central Hospital, Koblenz, Germany.ORCID http://orcid.org/0000-0002-0225-5950
Bingduo WangDepartment of Internal Medicine I, University Hospital of the Rheinische Friedrich Wilhelms University, Venusberg-Campus 1, 53127, Bonn, Germany.
Robert SchwabDepartment of General, Visceral and Thoracic Surgery, German Armed Forces Central Hospital, Koblenz, Germany.
Veronika Lukacs-KornekInstitute of Molecular Medicine and Experimental Immunology, University Hospital of the Rheinische Friedrich Wilhelms University, Bonn, Germany.ORCID http://orcid.org/0000-0002-6718-1219
Arnulf G WillmsDepartment of General, Visceral and Thoracic Surgery, German Armed Forces Central Hospital, Koblenz, Germany.ORCID http://orcid.org/0000-0001-9998-6735
Miroslaw T KornekDepartment of General, Visceral and Thoracic Surgery, German Armed Forces Central Hospital, Koblenz, Germany. miroslawkornek@web.de.ORCID http://orcid.org/0000-0002-1682-1765

Funding

Deutsche Forschungsgemeinschaft 410853455Deutsche Forschungsgemeinschaft 411345524German Armed forces (Bundeswehr) 31K1-S-10 2023
6 · The paper itself

Abstract

Liquid biomarkers are essential in trauma cases and critical care and offer valuable insights into the extent of injury, prognostic predictions, and treatment guidance. They can help assess the severity of organ damage (OD), assist in treatment decisions and forecast patient outcomes. Notably, small extracellular vesicles, particularly those involved in splenic trauma, have been overlooked. Here, we reanalyzed our data and explored whether monocyte-derived small EVs are correlated with AAST score (American Association for the Surgery of Trauma) scoring and are sensitive enough to distinguish the severity of splenic trauma in our explorative study. There was a correlation between monocyte-derived small extracellular vesicles (EVs) and the AAST score (r

Indexed as

SpleenWounds, NonpenetratingAdultBiomarkersExtracellular VesiclesFemaleHumansLiquid BiopsyMaleMiddle AgedMonocytesBiomarkersAASTBiomarkerBlunt splenic injuryExosomesExtracellular vesiclesLiquid biopsyNOMSpleen lacerationTrauma

Identifiers

PMID39754218
PMCPMC11699768

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.