Evidence map›Paper›PMID 39753867›Full record

ArticleMikrochimica acta2025

A colorimetric nano-enzyme assay with Ni@Pt nanoparticles as signal labels for rapid and sensitive detection of exosomal Aβ42 in plasma.

Junli Zhang, Yanyan Zhao, Haiying Hu, Min Lv, Hongling Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junli ZhangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Yanyan ZhaoSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Haiying HuSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Min LvSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Hongling ZhangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China. zhanghongling729@zzu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A nano-enzyme sandwich assay (SWzyme assay), a colorimetric system based on a biochip and inorganic nano-enzyme for rapid and simple determination of exosomal Aβ42 in plasma is proposed. Anti-CD63 antibody-modified biochips were prepared for plasma exosome capture and synthesized highly catalytic Ni@Pt nanozymes for detecting exosomal Aβ42. The method was able to detect exosomal Aβ42 with a limit of detection (LOD) as low as 4.2×10

Indexed as

Amyloid beta-PeptidesColorimetryExosomesLimit of DetectionMetal NanoparticlesNickelPlatinumAlzheimer DiseaseAnimalsHumansMicePeptide FragmentsAmyloid beta-Peptidesamyloid beta-protein (1-42)NickelPeptide FragmentsPlatinumAlzheimer’s diseaseBiochipColorimetricExosomal Aβ42Nanozymes

Identifiers

PMID39753867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.