ArticleScientific reports2025
Fracture properties of porcine versus human thoracic aortas from tricuspid/bicuspid aortic valve patients via symmetry-constraint Compact Tension testing.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Experimental Investigation into Bipolar Sealability of Elastin-Rich Tissue.Medical sciences (Basel, Switzerland) · 2026Article
- Tough and Rapidly Relaxing Hydrogels Via Programmable Crosslink Kinetics.Advanced materials (Deerfield Beach, Fla.) · 2026Article
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Authors and funding
7 authors.
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Abstract
Aneurysm rupture is a life-threatening event, yet its underlying mechanisms remain largely unclear. This study investigated the fracture properties of the thoracic aneurysmatic aorta (TAA) using the symmetry-constraint Compact Tension (symconCT) test and compared results to native and enzymatic-treated porcine aortas' tests. With age, the aortic stiffness increased, and tissues ruptured at lower fracture energy [Formula: see text]. Patients with bicuspid aortic valves were more sensitive to age, had stronger aortas and required more [Formula: see text] than tricuspid valves individuals (peak load: axial loading 4.42 ± 1.56 N vs 2.51 ± 1.60 N; circumferential loading 5.76 ± 2.43 N vs 4.82 ± 1.49 N. Fracture energy: axial loading 1.92 ± 0.60 kJ m
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