Evidence map›Paper›PMID 39753579›Full record

ArticleNPJ Parkinson's disease2025

Key shifts in frontoparietal network activity in Parkinson's disease.

Ronen Sosnik, Firas Fahoum, Zoya Katzir, Anat Mirelman, Inbal Maidan

Abstract read
In one paragraph

Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ronen SosnikFaculty of Electrical Engineering, Holon Institute of Technology (H.I.T.), Holon, Israel. ronens@hit.ac.il.
Firas FahoumBrain Electrophysiology and Epilepsy Lab (BEE-L), Epilepsy and EEG Unit, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.ORCID http://orcid.org/0000-0003-2262-5530
Zoya KatzirDepartment of Neurology, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Anat MirelmanDepartment of Neurology, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Inbal MaidanBrain Electrophysiology and Epilepsy Lab (BEE-L), Epilepsy and EEG Unit, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.ORCID http://orcid.org/0000-0001-7370-5798

Funding

Israel Science Foundation (ISF) 1157/20
6 · The paper itself

Abstract

We aimed to study the effect of Parkinson's disease (PD) and motor-cognitive load on the interplay between activation level and spatial complexity. To that end, 68 PD patients and 30 controls underwent electroencephalography (EEG) recording while executing visual single- and dual- Go/No-go tasks. The EEG underwent source localization, followed by parcellation of the neural activity into 116 regions of interest. We observed alterations in activity within a distributed network of brain areas associated with attention and inhibition operations, including a circuit pathway connecting frontal and temporal/parietal regions and the limbic network. The alterations in activity were associated with task complexity (single- or dual- task) and group (PD or controls) and encompassed spatial, temporal and spectral dimensions. These results elucidate electrophysiological alterations in four core aspects of brain activity associated with motor-cognitive function in PD patients and hold potential implications for future studies involving adaptive electrical interventions.

Identifiers

PMID39753579
PMCPMC11699216

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.