Evidence map›Paper›PMID 39753164›Full record

ArticleNeuroImage2025

Fast EEG/MEG BEM-based forward problem solution for high-resolution head models.

William A Wartman, Guillermo Nuñez Ponasso, Zhen Qi, Jens Haueisen, Burkhard Maess, Thomas R Knösche, Konstantin Weise, Gregory M Noetscher, Tommi Raij, Sergey N Makaroff

Abstract read
In one paragraph

Article in NeuroImage, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

William A WartmanDept. of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA, USA. Electronic address: wawartman@wpi.edu.
Guillermo Nuñez PonassoDept. of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA, USA.
Zhen QiDept. of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA, USA.
Jens HaueisenTechnische Universität Ilmenau, Institute of Biomedical Engineering and Informatics, Ilmenau, Germany.
Burkhard MaessMethods and Development Group 'Brain Networks', Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Thomas R KnöscheMethods and Development Group 'Brain Networks', Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Konstantin WeiseMethods and Development Group 'Brain Networks', Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Leipzig University of Applied Sciences (HTWK), Institute for Electrical Power Engineering, Leipzig, Germany.
Gregory M NoetscherDept. of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA, USA.
Tommi RaijAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA.
Sergey N MakaroffDept. of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA, USA.

Funding

Training and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Susie Yi Huang · 2020 to 2026
$10.9M
Re-Wiring the Human BrainR01NS126337 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Tommi Raij · 2022 to 2026
$3.4M
Charge-Based Brain Modeling Engine with Boundary Element Fast Multipole MethodR01MH130490 · NIMH · WORCESTER POLYTECHNIC INSTITUTE · PI Sergey N Makaroff · 2023 to 2026
$3.3M
Decoding parametric attributes of auditory working memories from human brain activityR01DC016915 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI AHVENINEN, JYRKI · 2018 to 2022
$3.0M
Non-invasive measures of multisensory cortical feedforward and feedback influencesR01DC016765 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI AHLFORS, SEPPO PENTTI, AHVENINEN, JYRKI · 2018 to 2022
$2.7M
CRSNS: Development of EEG/MEG Source Reconstruction with Fast Multipole MethodR01EB035484 · NIBIB · WORCESTER POLYTECHNIC INSTITUTE · PI Sergey N Makaroff · 2023 to 2026
$777k
CRCNS: Multifocal causal mapping of brain networks supporting human cognitionR01DC020891 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI NUMMENMAA, AAPO · 2022 to 2024
$756k
NIBIB NIH HHS P41 EB030006NIBIB NIH HHS R01 EB035484NIDCD NIH HHS R01 DC016765NIDCD NIH HHS R01 DC016915NIDCD NIH HHS R01 DC020891NIMH NIH HHS R01 MH130490NINDS NIH HHS R01 NS126337
6 · The paper itself

Abstract

A fast BEM (boundary element method) based approach is developed to solve an EEG/MEG forward problem for a modern high-resolution head model. The method utilizes a charge-based BEM accelerated by the fast multipole method (BEM-FMM) with an adaptive mesh pre-refinement method (called b-refinement) close to the singular dipole source(s). No costly matrix-filling or direct solution steps typical for the standard BEM are required; the method generates on-skin voltages as well as MEG magnetic fields for high-resolution head models within 90 s after initial model assembly using a regular workstation. The forward method is validated by comparison against an analytical solution on a spherical shell model as well as comparison against a full h-refinement method on realistic 1M facet human head models, both of which yield agreement to within 5 % for the EEG skin potential and MEG magnetic fields. The method is further applied to an EEG source localization (inverse) problem for real human data, and a reasonable source dipole distribution is found.

Indexed as

BrainBrain MappingElectroencephalographyHeadMagnetoencephalographyModels, NeurologicalAlgorithmsComputer SimulationHumansSignal Processing, Computer-AssistedAdaptive mesh refinement (AMR)Boundary Element Fast Multipole Method (BEM-FMM)Electroencephalography (EEG)Forward problemInverse problemMagnetoencephalography (MEG)

Identifiers

PMID39753164
PMCPMC11941539

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.