Article in Neurology(R) neuroimmunology & neuroinflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Javier Villacieros-ÁlvarezNeurology Department, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca.ORCID 0000-0002-5443-1434
Carmen EspejoNeurology Department, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca.ORCID 0000-0001-9949-5901
Georgina ArrambideNeurology Department, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca.ORCID 0000-0002-2657-5510
Alessandro DinotoNeurology Unit, Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0002-3249-4792
Patricia MuleroServicio de Neurología. Hospital Clínico Universitario de Valladolid.ORCID 0000-0001-8716-8997
Laura Rubio-FloresSynaptia Madrid Neurosciences, Vithas La Milagrosa, Aravaca & Arturo Soria University Hospitals, Madrid, Spain.ORCID 0000-0001-5570-8055
Pablo NietoServicio de Neurología, Hospital Universitario Rey Juan Carlos, Madrid, Spain.
Carmen AlcaláUnidad de Neuroinmunología, Hospital Universitari i Politècnic La Fe.
Jose E Meca-LallanaMultiple Sclerosis CSUR. Clinical Neuroimmunology Unit, Neurology Department, "Virgen de la Arrixaca" Clinical University Hospital, IMIB-Arrixaca, and NICEM Cathedra, UCAM-San Antonio Catholic University, Murcia, Spain.ORCID 0000-0001-5050-9890
Jorge Millan-PascualMultiple Sclerosis CSUR. Clinical Neuroimmunology Unit, Neurology Department, "Virgen de la Arrixaca" Clinical University Hospital, IMIB-Arrixaca, and NICEM Cathedra, UCAM-San Antonio Catholic University, Murcia, Spain.ORCID 0000-0003-2112-5964
Pedro Martínez-GarcíaImmunology Department, "Virgen de la Arrixaca" Clinical University Hospital, IMIB-Arrixaca, Murcia, Spain.
Raphael Bernard-ValnetService of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (Centre Hospitalier Universitaire Vaudois) and University of Lausanne, Switzerland.ORCID 0000-0001-7447-344X
Laura Navarro CantóNeurología. Hospital General Universitario de Elche, Alicante.
Silvia Presas-RodríguezMS-Neuroimmunology Unit, Neurosciences Department, Germans Trias i Pujol Hospital.
Sergio Martínez-YélamosMultiple Sclerosis Unit, Department of Neurology, Hospital Universitari de Bellvitge, Neurology and Neurogenetics Group, Neuroscience Program, Department of Clinical Sciences, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL).ORCID 0000-0001-9889-2040
Juan Pablo CuelloHospital General Universitario Gregorio Marañón.
Ana AlonsoHospital Regional Universitario de Málaga.
Raquel Piñar MoralesServicio de Neurologia. Hospital Universitario Clinico San Cecilio, Granada, Spain.ORCID 0000-0003-3490-4932
Gary Álvarez BravoUnitat de Neuroimmunologia i Esclerosi Múltiple Territorial Girona (UNIEMTG), Hospital Universitari de Girona Dr. Josep Trueta | Hospital Santa Caterina, Girona, Spain.ORCID 0000-0003-0342-0177
Lakhdar BenyahyaHospices Civils de Lyon, Service de Neurologie, Sclérose en Plaques, Pathologies de la Myéline et Neuro-Inflammation-Hôpital Neurologique Pierre Wertheimer, Bron Cedex.ORCID 0009-0005-0046-9487
Sophie Trouillet-AssantJoint Research Unit Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite.
Virginie Dyon-TafanJoint Research Unit Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite.
Caroline Froment TiliketeHospices Civils de Lyon, Service de Neuro-Ophtalmologie-Hôpital Neurologique Pierre Wertheimer, Bron Cedex.ORCID 0000-0002-1452-1398
Caroline PapeixDepartment of Neurology, AP-HP. Hôpital Pitié-Salpêtrière; Centre de Référence des Maladies Inflammatoires Rares du Cerveau et de la Moelle (MIRCEM), Paris.ORCID 0000-0003-4074-6125
Elisabeth MaillartDepartment of Neurology, AP-HP. Hôpital Pitié-Salpêtrière; Centre de Référence des Maladies Inflammatoires Rares du Cerveau et de la Moelle (MIRCEM), Paris.ORCID 0000-0001-7699-0328
Àlex RoviraSection of Neuroradiology, Department of Radiology (IDI), Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona.ORCID 0000-0002-2132-6750
Cristina AugerSection of Neuroradiology, Department of Radiology (IDI), Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona.ORCID 0000-0001-9846-4767
Bertrand AudoinAix Marseille Univ, APHM, Hôpital de la Timone, CNRS, CRMBM, Marseille, France; and.ORCID 0000-0002-9860-7657
Xavier MontalbanNeurology Department, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca.ORCID 0000-0002-0098-9918
Mar TintoreNeurology Department, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca.ORCID 0000-0001-9999-5359
Sara MariottoNeurology Unit, Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0002-7806-3103
Alvaro Cobo-CalvoNeurology Department, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca.ORCID 0000-0002-2574-0721
Romain MarignierHospices Civils de Lyon, Service de Neurologie, Sclérose en Plaques, Pathologies de la Myéline et Neuro-Inflammation-Hôpital Neurologique Pierre Wertheimer, Bron Cedex.ORCID 0000-0002-5967-2800
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
objectivesTo characterize the serum cytokine profile in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) at onset and during follow-up and assess their utility for predicting relapses and disability.
methodsThis retrospective multicentric cohort study included patients aged 16 years and older meeting MOGAD 2023 criteria, with serum samples collected at baseline (≤3 months from disease onset) and follow-up (≥6 months from the baseline), and age-matched and time to sampling-matched patients with multiple sclerosis (MS). Eleven cytokines were assessed using the ELLA system. Data comparisons and statistical analyses between cytokine levels and clinical outcomes were performed.
resultsEighty-eight patients with MOGAD and 32 patients with MS were included. Patients with MOGAD showed higher IL6 ( DISCUSSION: This study suggests a proinflammatory Th17-dominant profile in non-ON MOGAD patients, with a novel finding of a potential protective role of BAFF on relapses. These results shed new light on the pathogenesis of MOGAD, potentially guiding therapeutic decisions.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Profile and Usefulness of Serum Cytokines to Predict Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. · full record | OpenQuestion