Evidence map›Paper›PMID 39752400›Full record

ArticlePloS one2025

The association between helicobacter pylori infection and Triglyceride-Glucose (TyG) index in US adults: A retrospective cross-sectional study.

Wei Fu, Junlong Zhao, GuoBin Chen, Linya Lyu, Yao Ding, Liang-Bi Xu

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Association of TyG and TyG/HDL withFrontiers in medicine · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei FuDepartment of Gastroenterology, 925th Hospital of PLA Joint Logistics Support Force, Guiyang, China.ORCID 0000-0001-8155-431X
Junlong ZhaoDepartment of Medical Genetics and Developmental Biology, State Key Laboratory of Cancer Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
GuoBin ChenDepartment of Gastroenterology, 925th Hospital of PLA Joint Logistics Support Force, Guiyang, China.
Linya LyuDepartment of Gastroenterology, 925th Hospital of PLA Joint Logistics Support Force, Guiyang, China.ORCID 0009-0002-3345-7587
Yao DingDepartment of Gastroenterology, 925th Hospital of PLA Joint Logistics Support Force, Guiyang, China.
Liang-Bi XuDepartment of the Digestive Endoscopy, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Triglyceride-glucose (TyG) index is a marker for insulin resistance and metabolic syndrome, while Helicobacter pylori is linked to gastrointestinal diseases and may affect metabolic risks. This study examined the association between the TyG index and H. pylori infection in adults.

methodsData from 3797 participants in the NHANES 1999-2000 cycle were analyzed. The relationship between the TyG index and H. pylori infection was assessed using multivariate logistic regression and a two-piecewise logistic model to explore non-linear effects. Subgroup analyses were conducted based on age, sex, glucose levels, BMI, and CKD.

resultsA linear association between the TyG index and H. pylori infection was found. Subgroup analyses revealed significant interactions with a few variables.

conclusionsThis study indicates a linear relationship between the TyG index and H. pylori infection, suggesting metabolic influences on H. pylori infection and potential for targeted interventions in at-risk groups.

Indexed as

Blood GlucoseHelicobacter InfectionsHelicobacter pyloriTriglyceridesAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysRetrospective StudiesUnited StatesBlood GlucoseTriglycerides

Identifiers

PMID39752400
PMCPMC11698364

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.