Evidence map›Paper›PMID 39751818›Full record

ArticleCancer immunology, immunotherapy : CII2025

High CD38 expression defines a mitochondrial function-adapted CD8

Lei-Lei Lv, Jia-Wei Zhai, Jia-Juan Wu, Gui-Qin Fan, Yao-Xin Zhang, Yu Shen, Qiu-Xia Qu, Cheng Chen

Abstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei-Lei Lv *Department of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou, 215006, China.
Jia-Wei Zhai *Department of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou, 215006, China.
Jia-Juan Wu *Clinical Immunology Institute, the First Affiliated Hospital of Soochow University, 178 Ganjiang Road, Suzhou, 215006, China.
Gui-Qin FanRespiratory Department, Taicang Traditional Chinese Medicine Hospital, 140 Renmin South Road, Taicang, 215400, China.
Yao-Xin ZhangDepartment of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou, 215006, China.
Yu ShenClinical Immunology Institute, the First Affiliated Hospital of Soochow University, 178 Ganjiang Road, Suzhou, 215006, China.
Qiu-Xia QuClinical Immunology Institute, the First Affiliated Hospital of Soochow University, 178 Ganjiang Road, Suzhou, 215006, China. qxqu@suda.edu.cn.
Cheng ChenDepartment of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou, 215006, China. chencheng@suda.edu.cn.

Funding

National Natural Science Foundation of China 81672280National Natural Science Foundation of China 81874110Natural Science Foundation of Suzhou Municipality SYS2021034
6 · The paper itself

Abstract

Despite identifying specific CD8

Indexed as

ADP-ribosyl Cyclase 1CD8-Positive T-LymphocytesImmunotherapyLung NeoplasmsMitochondriaAnimalsCarcinoma, Non-Small-Cell LungCell Line, TumorFemaleHumansImmune Checkpoint InhibitorsMembrane GlycoproteinsMiceMice, Inbred C57BLT-Lymphocyte SubsetsTumor MicroenvironmentADP-ribosyl Cyclase 1CD38 protein, humanImmune Checkpoint InhibitorsMembrane GlycoproteinsCD38CD8+ T CellsImmune checkpoint blockadeLung cancerMitochondriaPD-1

Identifiers

PMID39751818
PMCPMC11699171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.