Evidence map›Paper›PMID 39750120›Full record

ArticleeLife2025

The

Kara A Nelson, Kari F Lenhart, Lauren Anllo, Stephen DiNardo

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Update of
    The2024
5 · Who and what money

Authors and funding

4 authors.

Kara A NelsonDepartment of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States.ORCID https://orcid.org/0000-0003-4847-2835
Kari F LenhartDepartment of Biology, Drexel University, Philadelphia, United States.
Lauren AnlloDepartment of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States.ORCID https://orcid.org/0000-0001-5482-5882
Stephen DiNardoDepartment of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States.ORCID https://orcid.org/0000-0003-4131-5511

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK · 2014 to 2026
$13.5M
Graduate Training in Developmental BiologyT32HD083185 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Michael Granato, Foteini Mourkioti · 2015 to 2026
$4.0M
Control of Stem Cell Dynamics by a Niche at Steady-State and During AgingR35GM136270 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DINARDO, STEPHEN FRANCIS · 2020 to 2024
$2.1M
Mechanisms governing stem cell coordination by the nicheR01GM138705 · NIGMS · DREXEL UNIVERSITY · PI LENHART, KARI · 2020 to 2024
$1.8M
Imaging the formation of an hematopoietic nicheR03HD111973 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI DINARDO, STEPHEN FRANCIS · 2023 to 2023
$163k
The signals and cell mechanics driving stem cell niche morphogenesisF32GM125123 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ANLLO, LAUREN M. · 2018 to 2019
$120k
Mechanism of niche formation, and impact of niche position on tissue functionF31HD111208 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI NELSON, KARA · 2022 to 2024
$105k
Eunice Kennedy Shriver National Institute of Child Health and Human Development HD083185Eunice Kennedy Shriver National Institute of Child Health and Human Development HD111208Eunice Kennedy Shriver National Institute of Child Health and Human Development HD111973NICHD NIH HHS F31 HD111208NICHD NIH HHS R03 HD111973NICHD NIH HHS T32 HD083185NIGMS NIH HHS F32 GM125123NIGMS NIH HHS GM125123NIGMS NIH HHS GM136270NIGMS NIH HHS GM138705NIGMS NIH HHS R01 GM138705NIGMS NIH HHS R35 GM136270NIH HHS P40 OD018537
6 · The paper itself

Abstract

Niches are often found in specific positions in tissues relative to the stem cells they support. Consistency of niche position suggests that placement is important for niche function. However, the complexity of most niches has precluded a thorough understanding of how their proper placement is established. To address this, we investigated the formation of a genetically tractable niche, the

Indexed as

Cell MovementDrosophila melanogasterDrosophila ProteinsNerve Tissue ProteinsReceptors, ImmunologicRoundabout ProteinsSignal TransductionStem Cell NicheAnimalsDrosophilaHematopoietic Stem CellsReceptors, Invertebrate PeptideReceptors, NotchDrosophila ProteinsNerve Tissue ProteinsN protein, DrosophilaReceptors, ImmunologicReceptors, Invertebrate PeptideReceptors, NotchRoundabout Proteinssli protein, Drosophilacell migrationdevelopmental biologyD. melanogasterDrosophilahematopoietic nicheorganogenesisregenerative medicineslit-robostem cells

Identifiers

PMID39750120
PMCPMC11698496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.