Evidence map›Paper›PMID 39749982›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2024

The Cumulative Burden of Social Risk Factors and 10-Year Change in Quality of Life.

Ro-Jay Reid, Monika Safford, W Marcus Lambert, Joanna Bryan, Laura C Pinheiro, Madeline R Sterling, C Barrett Bowling, Emily B Levitan, Samprit Banerjee, Raegan Durant and 3 more

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ro-Jay ReidDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-5279-4872
Monika SaffordDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.
W Marcus LambertDepartment of Epidemiology and Biostatistics, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Joanna BryanDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.
Laura C PinheiroDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.
Madeline R SterlingDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-9928-4407
C Barrett BowlingDepartment of Medicine, Durham Veterans Affairs Geriatric Research Education and Clinical Center, Durham Veterans Affairs Health Care System (VAHCS), Duke University, Durham, North Carolina, USA.
Emily B LevitanDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-5429-3852
Samprit BanerjeeDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Raegan DurantDivision of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Michael KimDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-0087-0199
Jennifer D LauDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.
Parag GoyalDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0001-7474-3737

Funding

REGARDS - MI StudyR01HL080477 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2006 to 2020
$11.6M
REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction-4 (REGARDS-MI-4)R01HL165452 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2022 to 2025
$8.3M
Clinical Research Scholars Training (CREST) ProgramR25MD017950 · NIMHD · SUNY DOWNSTATE MEDICAL CENTER · PI Carla Boutin-Foster, Marlene Camacho · 2022 to 2026
$2.6M
American Heart Association 20CDA35310455Department of Health and Human ServiceHealth Resources Services Administration T32HP4201-01-00NHLBI NIH HHS R01 HL080477NHLBI NIH HHS R01 HL165452NHLBI NIH HHS R01 HL80477NIA NIH HHSNIH HHSNIMHD NIH HHS R25 MD017950NINDS NIH HHS
6 · The paper itself

Abstract

backgroundSocial risk factors are linked to adverse health outcomes, but their total impact on long-term quality of life is obscure. We hypothesized that a higher burden of social risk factors is associated with greater decline in quality of life over 10 years.

methodsWe examined associations between social risk factors count and decline >5 points in (i) physical component summary, and (ii) mental component summary scores from the Short Form-12 among Black and White participants in the Reasons for Geographic and Racial Differences in Stroke study (n = 14 401).

resultsFor physical component summary, White participants with 1 social risk factor had relative risk (RR) for decline of 1.14 [95% confidence intervals (CI): 1.07-1.12]. Those with ≥2 social risk factors had RR of 1.26 [95% CI: 1.17-1.35], after adjusting for baseline demographics, health behaviors, medical conditions, medications, and physiological variables. Black participants with 1 social risk factor had RR of 1.03 [95% CI: 0.93-1.15]. Those with ≥2 social risk factors had RR of 1.24 [95% CI: 1.13-1.36]. For mental component summary, White participants with 1 social risk factor had RR for decline of 1.19 [95% CI: 1.04-1.37]. Those with ≥2 social risk factors had RR of 1.47 [95% CI: 1.28-1.68]. Black participants with 1 social risk factor had RR of 1.18 [95% CI: 0.96-1.45]. Those with ≥2 social risk factors had RR of 1.38 [95% CI: 1.14-1.66].

conclusionsMore social risk factors increased the risk of decline of quality of life for Black and White individuals, especially impacting mental health.

Indexed as

Quality of LifeAgedBlack or African AmericanFemaleHumansMaleMiddle AgedRisk FactorsSocial Determinants of HealthUnited StatesWhite12-Item Short Form 12 (SF-12)Mental component summary (MCS) scoresPhysical component summary (PCS) scores

Identifiers

PMID39749982
PMCPMC11697184

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.