Evidence map›Paper›PMID 39749835›Full record

ArticleJournal of the American Chemical Society2025

A Single Bioorthogonal Reaction for Multiplex Cell Surface Protein Labeling.

Yang Huang, Chengyang Wu, Anjing Lu, Jingzhe Wang, Jian Liang, Han Sun, Liqing Yang, Shixiang Duan, Andrey A Berezin, Chuanliu Wu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yang HuangSchool of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.ORCID 0000-0002-7542-8074
Chengyang WuSchool of Chemistry, Cardiff University, Cardiff CF10 3AT, United Kingdom.ORCID 0009-0002-9411-4318
Anjing LuInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Jingzhe WangInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Jian LiangInstitute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Han SunInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Liqing YangInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Shixiang DuanInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Andrey A BerezinSchool of Chemistry, Cardiff University, Cardiff CF10 3AT, United Kingdom.
Chuanliu WuDepartment of Chemistry, College of Chemistry and Chemical Engineering, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, State Key Laboratory of Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen 361005, China.ORCID 0000-0003-2946-7299
Bo ZhangInstitute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Yi-Lin WuSchool of Chemistry, Cardiff University, Cardiff CF10 3AT, United Kingdom.ORCID 0000-0003-0253-1625
Yu-Hsuan TsaiInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen 518132, China.ORCID 0000-0003-0589-5088

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small-molecule fluorophores are invaluable tools for fluorescence imaging. However, means for their covalent conjugation to the target proteins limit applications in multicolor imaging. Here, we identify 2-[(alkyl

Indexed as

Fluorescent DyesMembrane ProteinsAnimalsAzidesCycloaddition ReactionHumansMiceMolecular StructureOptical ImagingAzidesFluorescent DyesMembrane Proteins

Identifiers

PMID39749835
PMCPMC11744750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.