Evidence map›Paper›PMID 39749685›Full record

ArticleCancer communications (London, England)2025

Multiscale 3D spatial analysis of the tumor microenvironment using whole-tissue digital histopathology.

Daniel Shafiee Kermany, Ju Young Ahn, Matthew Vasquez, Weijie Zhang, Lin Wang, Kai Liu, Zhan Xu, Min Soon Cho, Wendolyn Carlos-Alcalde, Hani Lee and 7 more

Abstract read
In one paragraph

Article in Cancer communications (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Daniel Shafiee Kermany *Translational Biophotonics Laboratory, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.
Ju Young Ahn *Ting Tsung & Wei Fong Chao Center for BRAIN, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.
Matthew VasquezTing Tsung & Wei Fong Chao Center for BRAIN, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.
Weijie ZhangLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, USA.
Lin WangTing Tsung & Wei Fong Chao Center for BRAIN, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.
Kai LiuTing Tsung & Wei Fong Chao Center for BRAIN, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.
Zhan XuLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, USA.
Min Soon ChoDepartment of Pulmonary Medicine, Division of Internal Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Wendolyn Carlos-AlcaldeDepartment of Pulmonary Medicine, Division of Internal Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Hani LeeDepartment of Pulmonary Medicine, Division of Internal Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Raksha RaghunathanTranslational Biophotonics Laboratory, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.
Jianting ShengTing Tsung & Wei Fong Chao Center for BRAIN, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.
Xiaoxin HaoLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, USA.
Hong ZhaoTing Tsung & Wei Fong Chao Center for BRAIN, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.
Vahid Afshar-KharghanDepartment of Pulmonary Medicine, Division of Internal Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Xiang Hong-Fei ZhangLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, USA.
Stephen Tin Chi WongTranslational Biophotonics Laboratory, Department of Systems Medicine and Bioengineering, Houston Methodist Neal Cancer Center, Houston, Texas, USA.ORCID https://orcid.org/0000-0001-9188-6502

Funding

Platelets promote growth of ovarian cancerR01CA177909 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI AFSHAR-KHARGHAN, VAHID, SOOD, ANIL K · 2013 to 2023
$4.1M
Osteoclast-Independent Mechanisms of Early-Stage Bone Colonization of Breast CancerR01CA183878 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ZHANG, XIANG · 2014 to 2024
$3.5M
Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumorsR01CA238727 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WONG, STEPHEN TC, ZHAO, HONG · 2020 to 2024
$2.6M
Unveiling the mechanisms underlying secondary metastasis and possible therapeutic windowsR01CA251950 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ZHANG, XIANG · 2020 to 2024
$2.6M
To study the EMT contributions in tumor metastasis and chemoresistance by using lineage tracing modelsR01CA244413 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GAO, DINGCHENG · 2020 to 2024
$2.4M
Novel Biomarkers Predicting Blood Clots in Ovarian CancerR01CA275762 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Vahid Afshar-Kharghan, ANIL K SOOD · 2023 to 2026
$1.9M
Genetics of Graft-versus-Host DiseaseR01CA231141 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI AFSHAR-KHARGHAN, VAHID, GORLOVA, OLGA · 2018 to 2022
$1.6M
Breast Cancer Research FoundationJohn S. Dunn FoundationJohn S. Dunn Research FoundationMcNair Medical InstituteNCI NIH HHS R01CA016672NCI NIH HHS R01CA177909NCI NIH HHS R01CA183878NCI NIH HHS R01 CA231141NCI NIH HHS R01CA238727NCI NIH HHS R01CA244413NCI NIH HHS R01CA251950NCI NIH HHS R01CA275762NCI NIH HHS U01CA252553Ting Tsung and Wei Fong Chao Family FoundationU.S. Department of Defense W81XWH-16-1-0073U.S. Department of Defense W81XWH-20-1-0375US Department of Defense DAMD W81XWH-16-1-0073Wei Fong Chao Foundation
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39749685
PMCPMC11947609

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.