Evidence map›Paper›PMID 39749675›Full record

ArticleeLife2025

Capsular polysaccharide restrains type VI secretion in

Nicolas Flaugnatti, Loriane Bader, Mary Croisier-Coeytaux, Melanie Blokesch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicolas FlaugnattiLaboratory of Molecular Microbiology, Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-6073-3340
Loriane BaderLaboratory of Molecular Microbiology, Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Mary Croisier-CoeytauxBioelectron Microscopy Core Facility, School of Life Sciences, Station 19, EPFL-SV-PTBIOEM, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Melanie BlokeschLaboratory of Molecular Microbiology, Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-7024-1489

Funding

Howard Hughes Medical Institute 55008726Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_204335Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 407240_167061
6 · The paper itself

Abstract

The type VI secretion system (T6SS) is a sophisticated, contact-dependent nanomachine involved in interbacterial competition. To function effectively, the T6SS must penetrate the membranes of both attacker and target bacteria. Structures associated with the cell envelope, like polysaccharides chains, can therefore introduce spatial separation and steric hindrance, potentially affecting the efficacy of the T6SS. In this study, we examined how the capsular polysaccharide (CPS) of

Indexed as

Acinetobacter baumanniiBacterial CapsulesPolysaccharides, BacterialType VI Secretion SystemsBacterial ProteinsBacterial ProteinsPolysaccharides, BacterialType VI Secretion SystemsAcinetobacter baumanniicapsular polysaccharideimmunity protein-independent protectioninfectious diseasemicrobiologytype VI secretion

Identifiers

PMID39749675
PMCPMC11731876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.