Evidence map›Paper›PMID 39749457›Full record

ArticleSchizophrenia bulletin2026

Examining Psychosis Risk in Sexual Minority Youth: Increased Exposure to and Differential Impact of the Social Envirome in Early Adolescence.

Margaux Sageot, Inez Myin-Germeys, Robin Achterhof, Ruud van Winkel

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Margaux SageotDepartment of Neurosciences, Research Group Psychiatry, Center for Clinical Psychiatry, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-5102-8351
Inez Myin-GermeysDepartment of Neurosciences, Research Group Psychiatry, Center for Contextual Psychiatry, KU Leuven, 3000 Leuven, Belgium.
Robin AchterhofDepartment of Neurosciences, Research Group Psychiatry, Center for Contextual Psychiatry, KU Leuven, 3000 Leuven, Belgium.
Ruud van WinkelDepartment of Neurosciences, Research Group Psychiatry, Center for Clinical Psychiatry, KU Leuven, 3000 Leuven, Belgium.

Funding

Julie Renson, Queen Fabiola and King Baudoin FoundationResearch Foundation Flanders Odysseus FWO G049219NResearch Foundation Flanders Senior Clinical Fellowship FWO 1803616 N
6 · The paper itself

Abstract

background and hypothesesSexual minority populations have a higher prevalence of psychotic experiences (PE), possibly due to differential experiences within the social envirome in its positive (eg, social support, parenting) and negative aspects (eg, adverse life events, bullying). This study hypothesized that (1) sexual minority adolescents experience more PE, (2) are more exposed to harmful aspects of the social envirome, and (3) may display differential sensitivity to certain aspects of the social envirome. STUDY

designData from 678 adolescents (mean age 15.6 years) were analyzed. Psychotic experiences were assessed using the Prodromal Questionnaire 16 (PQ-16). Aspects of the social envirome (childhood adversity, bullying, parenting style, and social support) were evaluated using different questionnaires. STUDY

resultsThe odds ratio of having sexual minority status (SMS) was 1.98 (95 CI%, 1.02-3.84) for participants with PE (PQ-16 ≥ 6) compared to participants without. Significant associations were found between SMS and more adverse childhood experiences (95% CI, 0.11-3.51) and parenting psychological control (95% CI, 0.11-0.53), and less parenting autonomy support (95% CI, -0.37 to -0.01). There were also significant differential effects: adverse childhood experiences were associated with PE in heterosexuals but not in sexual minorities (95% CI, -0.34 to -0.03), while less social support was associated with more PE in heterosexuals but less PE in sexual minorities (95% CI, 0.06-0.39).

conclusionsSexual minority status is associated with a higher prevalence of PE, greater exposure to harmful factors within the social envirome, and differential effects on sexual minority and heterosexual individuals. These results emphasize the need for a fine-grained analysis of the envirome to understand the increased risk for PE in sexual minorities.

Indexed as

Adverse Childhood ExperiencesBullyingParentingPsychotic DisordersSexual and Gender MinoritiesSocial SupportAdolescentFemaleHumansMaleRiskpsychotic experiencessensitizationsexual minority statussocial environment

Identifiers

PMID39749457
PMCPMC12809844

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.