Observational studyJournal of rehabilitation medicine2025
Eye tracking to support assessment of patients with prolonged disorder of consciousness - a case series.
Observational study in Journal of rehabilitation medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Eye-Tracking Technologies for Cognitive Assessment After Acquired Brain Injury: Systematic Review.JMIR rehabilitation and assistive technologies · 2026Review
- Eye-Tracking Assessment in Patients with Disorders of Consciousness: A Systematic Review.Brain sciences · 2026Review
- Eye movements as indicators of awareness in prolonged disorders of consciousness: a scoping review of behavioral and neural evidence.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate if eye tracking can support detection of covert voluntary eye movements and to compare these findings with a simultaneously performed clinical assessment according to the Coma Recovery Scale manual regarding visual stimuli.
designObservational case series. SUBJECTS: Twelve outpatients with prolonged disorders of consciousness recruited from the rehabilitation clinic of a regional rehabilitation unit.
methodEye movements were recorded with a wearable eye tracker while performing 4 test items from the Coma Recovery Scale Revised. The clinical assessment and recorded eye movement responses were analysed for agreement.
resultsResponse data was obtained from 238 out of 288 trials. Eye-tracking data were obtained in median 89.6% of the trials (37.5-100%). The eye tracking assessment judged a significantly higher percentage of trials as a response (46.2%) compared with the clinical assessment (18.1%), mainly in test items "visual pursuit" and "visual fixation".
conclusionEye tracking showed potential to be more effective in the detection of putative voluntary eye movements compared with conventional examination. Based on the findings in this and previous studies, eye tracking may serve as a useful complementary tool when examining patients with prolonged disorders of consciousness.
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