Evidence map›Paper›PMID 39749402›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2025

The new thiazolidine-2,4-dione-based hybrids with promising antimycobacterial activity: design, synthesis, biological evaluation, and drug interaction analysis.

Nazar Trotsko, Agnieszka Głogowska, Barbara Kaproń, Katarzyna Kozieł, Ewa Augustynowicz-Kopeć, Agata Paneth

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nazar TrotskoDepartment of Organic Chemistry, Medical University of Lublin, Lublin, Poland.
Agnieszka GłogowskaDepartment of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland.
Barbara KaprońDepartment of Clinical Genetics, Medical University of Lublin, Lublin, Poland.
Katarzyna KoziełDepartment of Organic Chemistry, Students Research Group, Medical University of Lublin, Lublin, Poland.
Ewa Augustynowicz-KopećDepartment of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland.
Agata PanethDepartment of Organic Chemistry, Medical University of Lublin, Lublin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ever-increasing drug-resistant tuberculosis (TB) has invigorated the focus on the discovery and development of novel therapeutic agents and treatment options. Thiazolidinone-based compounds have shown good antitubercular properties

Indexed as

Antitubercular AgentsDose-Response Relationship, DrugDrug DesignMicrobial Sensitivity TestsMycobacterium tuberculosisThiazolidinedionesDrug InteractionsMolecular StructureStructure-Activity RelationshipAntitubercular Agentsthiazolidine-2,4-dioneThiazolidinedionesantimycobacterial activitycytotoxicitystructure–activity relationshipsynergismThiazolidine-2,4-diones

Identifiers

PMID39749402
PMCPMC11703137

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.