Evidence map›Paper›PMID 39749204›Full record

ArticleFrontiers in pharmacology2024

Comparison of the composition, immunological activity and anti-fatigue effects of different parts in sika deer antler.

Siqi Chen, Yidan Li, Yichun Yang, Shibo Zhao, Huali Shi, Chengkai Yang, Min Wu, Aiwu Zhang

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siqi ChenCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Yidan LiCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Yichun YangCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Shibo ZhaoCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Huali ShiCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Chengkai YangCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Min WuCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Aiwu ZhangCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sika deer ( Methods: The contents of protein, amino acids, polysaccharides, phospholipids, minerals and nucleotides in wax, powder, gauze and bone slices were determined by different nutrient assays. Then, 100 mice were randomly divided into 5 groups. The mice in control group were administered 0.3 mL of saline solution per day. The mice in experimental groups were administered 0.3 mL enzymatic hydrolysate of the wax slice, powder slice, gauze slice, bone slice separately per day, continuously for 14 days from the first day. The effect of antler on boosting immunity was evaluated by testing organ indices and assessing immunoglobulin levels by ELISA. Anti-fatigue effects were assessed by a mouse swimming test. Finally, the correlation between composition and pharmacological effects was analysed. Results: The content of each marker substance gradually decreases from the upper to the basal of deer antler. The protein and uracil content in the wax slice were significantly higher than the other three groups ( Conclusion: These outcomes indicated that the wax slice yielded optimal results among the tested parts and demonstrated the highest efficacy.

Indexed as

anti-fatigue effectcompositionimmunological activitysika deer antlertraditional medicine

Identifiers

PMID39749204
PMCPMC11693646

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.