Evidence map›Paper›PMID 39749159›Full record

ArticleInfection and drug resistance2024

Clinical Differences Between Survivors and Non-Survivors of Ventilator-Associated Pneumonia: The Roles of Sulbactam/Ampicillin and Methicillin-Resistant

Masafumi Seki, Anna Takimoto, Manabu Inoue, Kazuya Niiyama, Ayumu Masuoka, Futoshi Kotajima

Abstract read
In one paragraph

Article in Infection and drug resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masafumi SekiDivision of Infectious Diseases and Infection Control, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.ORCID 0000-0001-5414-8148
Anna TakimotoRespiratory Support Team, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Manabu InoueRespiratory Support Team, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Kazuya NiiyamaRespiratory Support Team, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Ayumu MasuokaRespiratory Support Team, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Futoshi KotajimaRespiratory Support Team, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ventilator-associated pneumonia (VAP) is one of the most lethal complications in intensive care unit (ICU) patients. However, critical issues of non-survivors vary and are still unclear in VAP patients. Methods: The clinical differences between survivors and non-survivors of VAP were retrospectively analyzed in patients hospitalized from April 2023 to March 2024. Results: Of a total of 42 VAP patients, 22 (52.4%) survived, and 20 died. Survivors were significantly younger (69.1 vs 71.7 years, p < 0.01) and received sulbactam/ampicillin (SAM) as the initial antibiotics, significantly more (45.5% vs 10%, p = 0.006) than non-survivors. The male/female ratio and wards where they were managed were similar in both groups, but methicillin-resistant Conclusion: These data suggest that VAP patients who survived were younger and received treatment with narrow-spectrum antibiotics, such as SAM. Isolation of MRSA might be critical. These findings could influence antibiotic protocols and ICU management strategies to prevent infection with resistant bacteria to improve the prognosis of patients with VAP.

Indexed as

Methicillin-resistant Staphylococcus aureusPseudomonas aeruginosasulbactam/ampicillinvancomycinventilator-associated pneumonia

Identifiers

PMID39749159
PMCPMC11693857

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.