Evidence map›Paper›PMID 39748983›Full record

ArticleHeliyon2024

Genomics-based timely detection of dengue virus type I genotypes I and V in Uruguay.

Noelia Morel, Marta Giovanetti, Vagner Fonseca, Analía Burgueño, Mauricio Lima, Emerson Castro, Natália R Guimarães, Felipe C M Iani, Victoria Bormida, Maria Noel Cortinas and 9 more

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Tracing Dengue's Evolutionary and Phylogenetic Pathways.Current topics in microbiology and immunology · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Noelia MorelLaboratorio de Virus Emergentes/reemergentes. Unidad de Virología, Departamento de Laboratorios de Salud Pública, Portugal.
Marta GiovanettiSciences and Technologies for Sustainable Development and One Health, Universita Campus Bio-Medico di Roma, Italy.
Vagner FonsecaInstituto Rene Rachou, Fundação Oswaldo Cruz, Minas Gerais, Brazil.
Analía BurgueñoLaboratorio de Virus Emergentes/reemergentes. Unidad de Virología, Departamento de Laboratorios de Salud Pública, Portugal.
Mauricio LimaLaboratorio Central de Saúde Pública do Estado de Minas Gerais, Fundação Ezequiel Dias, Brazil.
Emerson CastroLaboratorio Central de Saúde Pública do Estado de Minas Gerais, Fundação Ezequiel Dias, Brazil.
Natália R GuimarãesLaboratorio Central de Saúde Pública do Estado de Minas Gerais, Fundação Ezequiel Dias, Brazil.
Felipe C M IaniLaboratorio Central de Saúde Pública do Estado de Minas Gerais, Fundação Ezequiel Dias, Brazil.
Victoria BormidaUnidad de Genómica. Depto. De Laboratorios de Salud Pública, Uruguay.
Maria Noel CortinasUnidad de Genómica. Depto. De Laboratorios de Salud Pública, Uruguay.
Viviana RamasLaboratorio de Virus Respiratorios, Unidad de Virología. Departamento de Laboratorios de Salud Pública, Uruguay.
Leticia CoppolaLaboratorio de Virus Respiratorios, Unidad de Virología. Departamento de Laboratorios de Salud Pública, Uruguay.
Ana I BentoPandemic Prevention Initiative, The Rockefeller Foundation, Washington DC, USA.
Alexander RosewellCoordenação de Vigilância, Preparação e Resposta à Emergências e Desastres (PHE), Organização Pan-Americana da Saúde / Organização Mundial da Saúde (OPAS/OMS), Brasília, DF, Brazil.
Leticia FrancoInfectious Hazards Management, Health Emergencies Department (PHE), Pan American Health Organization / World Health Organization (PAHO/WHO), Washington DC, USA.
Jairo Mendez RicoInfectious Hazards Management, Health Emergencies Department (PHE), Pan American Health Organization / World Health Organization (PAHO/WHO), Washington DC, USA.
José LourençoBioISI (Biosystems and Integrative Sciences Institute), Faculdade de Ciências da Universidade de Lisboa, Portugal.
Luiz Carlos Junior AlcantaraInstituto Rene Rachou, Fundação Oswaldo Cruz, Minas Gerais, Brazil.
Hector ChiparelliLaboratorio de Virus Emergentes/reemergentes. Unidad de Virología, Departamento de Laboratorios de Salud Pública, Portugal.

Funding

University of Washington Arboviral Research Network (UWARN)U01AI151698 · NIAID · UNIVERSITY OF WASHINGTON · PI Michael Gale, PETER MACGARR RABINOWITZ · 2020 to 2026
$13.3M
NIAID NIH HHS U01 AI151698World Health Organization 001
6 · The paper itself

Abstract

This study details a genomics-based approach for the early detection of mosquito-borne pathogens, marked by Uruguay's first ever complete genomic sequencing of Dengue Virus type I genotypes I and V. This pioneering effort has facilitated the prompt identification of these genotypes within the country, enabling Uruguayan public health authorities to develop timely and effective response strategies. Further integrated into this approach is a climate-driven suitability measure, closely associated with Dengue case reports and indicative of the local climate's role in the virus's transmission in the country within the changing climate context. The detection of multiple DENV-1 genotypes co-circulating in Uruguay underscores the necessity for proactive surveillance, particularly at borders, to prevent the introduction and dissemination of novel viral strains within the country and the region. This approach aids in facilitating prompt public health responses and intervention strategies, which are crucial in mitigating the impact of dengue outbreaks.

Indexed as

Dengue virusGenomic monitoringSouth AmericaUruguay

Identifiers

PMID39748983
PMCPMC11693888

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.