Evidence map›Paper›PMID 39748857›Full record

ArticleFrontiers in neurology2024

Low-density scalp electrical source imaging of the ictal onset zone network using source coherence maps.

Parnia Sadeghzadeh, Alexander Freibauer, Rajesh RamachandranNair, Robyn Whitney, Mutaz Al Nassar, Puneet Jain, Elizabeth Donner, Ayako Ochi, Kevin C Jones

Abstract read
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In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Parnia SadeghzadehDivision of Neurology, Department of Pediatrics, McMaster Children's Hospital, Hamilton, ON, Canada.
Alexander FreibauerDivision of Neurology, Department of Pediatrics, BC Children's Hospital, Vancouver, BC, Canada.
Rajesh RamachandranNairDivision of Neurology, Department of Pediatrics, McMaster Children's Hospital, Hamilton, ON, Canada.
Robyn WhitneyDivision of Neurology, Department of Pediatrics, McMaster Children's Hospital, Hamilton, ON, Canada.
Mutaz Al NassarDivision of Neuroimaging, Department of Diagnostic Imaging, McMaster Children's Hospital, Hamilton, ON, Canada.
Puneet JainDivision of Neurology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada.
Elizabeth DonnerDivision of Neurology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada.
Ayako OchiDivision of Neurology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada.
Kevin C JonesDivision of Neurology, Department of Pediatrics, McMaster Children's Hospital, Hamilton, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study investigated low-density scalp electrical source imaging of the ictal onset zone and interictal spike ripple high-frequency oscillation networks using source coherence maps in the pediatric epilepsy surgical workup. Intracranial monitoring, the gold standard for determining epileptogenic zones, has limited spatial sampling. Source coherence analysis presents a promising new non-invasive technique. Methods: This was a retrospective review of 12 patients who underwent focal resections. Source coherence maps were generated using standardized low-resolution electromagnetic tomography and concordance to resection margins was assessed, noting outcomes at 3 years post-surgery. Results: Ictal source coherence maps were performed in 7/12 patients. Six of seven included the surgical resection. Five of seven cases were seizure free post-resection. Interictal spike ripple electrical source imaging and interictal spike ripple high-frequency oscillation networks using source coherence maps were performed for three cases, with two of three included in the resection and all three were seizure free. Discussion: These findings may provide proof of principle supporting low-density scalp electrical source imaging of the ictal onset zone and spike ripple network using source coherence maps. This promising method is complementary to ictal and interictal electrical source imaging in the pediatric epilepsy surgical workup, guiding electrode placement for intracranial monitoring to identify the epileptogenic zone.

Indexed as

electrical source imagingepilepsy surgeryictal onset zonelow densitysource coherence maps

Identifiers

PMID39748857
PMCPMC11693594

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.