Evidence map›Paper›PMID 39748840›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)

The African Initiative for Bioinformatics Online Training in Neurodegenerative Diseases (AI-BOND): Investing in the next generation of African neuroscientists.

Bernard Fongang, Biniyam A Ayele, Yannick N Wadop, Emmanuel Epenge, Cyrille D Nkouonlack, Wepnyu Y Njamnshi, Xueqiu Jian, Murali Sargurupremraj, Alice B S Nono Djotsa, Paul F Seke Etet and 8 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Bernard FongangGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA.ORCID https://orcid.org/0000-0002-8161-1553
Biniyam A AyeleJohn P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA.
Yannick N WadopGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA.ORCID https://orcid.org/0000-0002-8955-1874
Emmanuel EpengeUniversité Protestante Au Congo. M78W+MX2 Croisement des avenues de Libération Kinshasa Democratic Republic of the Congo.
Cyrille D NkouonlackBrain Research Africa Initiative (BRAIN) Geneva, Switzerland & Yaoundé, Obobogo Yaoundé Cameroon.
Wepnyu Y NjamnshiBrain Research Africa Initiative (BRAIN) Geneva, Switzerland & Yaoundé, Obobogo Yaoundé Cameroon.
Xueqiu JianGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA.
Murali SargurupremrajGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA.
Alice B S Nono DjotsaDepartment of Medicine Section of Health Services Research Baylor College of Medicine Houston Texas USA.
Paul F Seke EtetBrain Research Africa Initiative (BRAIN) Geneva, Switzerland & Yaoundé, Obobogo Yaoundé Cameroon.
Rebecca BernalGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA.
Abdon AtanganaNatural and Agricultural Sciences, Institute of Groundwater Studies University of Free State Bloemfontein South Africa.
Jose E CavazosGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA.
Jayandra Jung HimaliGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA.
Alfred N FontehNeuroscience Department Huntington Medical Research Institute Pasadena California USA.
Gladys MaestreDepartment of Neurosciences and Department of Human Genetics University of Texas Rio Grande Valley School of Medicine Edinburg Texas USA.
Alfred K NjamnshiBrain Research Africa Initiative (BRAIN) Geneva, Switzerland & Yaoundé, Obobogo Yaoundé Cameroon.ORCID https://orcid.org/0000-0003-0052-1511
Sudha SeshadriGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA.

Funding

Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)U19AG074865 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GOLDIE S. BYRD, William S Bush · 2022 to 2026
$55.3M
South Texas Alzheimer's Disease Research CenterP30AG066546 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Mohamad Habes · 2021 to 2026
$24.0M
Rio Grande Valley Alzheimer's Resource Center for Minority Aging Research: Partnerships for ProgressP30AG059305 · NIA · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI Gladys E. Maestre · 2018 to 2026
$5.8M
Delineating the role of the gut microbiota and its derived metabolites in the development of dementia in multi-ethnic populationsK01NS126489 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Bernard Fongang · 2023 to 2026
$882k
NIA NIH HHS P30 AG059305NIA NIH HHS P30 AG066546NIA NIH HHS U19 AG074865NINDS NIH HHS K01 NS126489
6 · The paper itself

Abstract

Neurodegenerative disorders, including Alzheimer's disease and AD-related dementias (AD/ADRD), pose significant challenges to health care systems globally, particularly in Africa. With the advances in medical technology and research capabilities, especially in next-generation sequencing and imaging, vast amounts of data have been generated from AD/ADRD research. Given that the greatest increase in AD/ADRD prevalence is expected to occur in Africa, it is critical to establish comprehensive bioinformatics training programs to help African scientists leverage existing data and collect additional information to untangle AD/ADRD heterogeneity in African populations. The South Texas Alzheimer's Disease Research Center, with efforts from the National Institutes of Health and the Global Brain Health Institute, has partnered with the Brain Research Africa Initiative to develop the Highlights: Alzheimer's disease (AD) and AD-related dementias (ADRD) pose significant health challenges globally, particularly in Africa.The most significant AD/ADRD prevalence increase is predicted to occur in Africa.It is crucial to establish a bioinformatics training capacity in Africa to leverage the vast number of multi-omics and imaging biomarkers of AD/ADRD data being generated.The African Initiative on Bioinformatics Online Training in Neurodegenerative Disease (AI-BOND) training addresses the gaps in study design, biostatistics, genetic epidemiology, and bioinformatics related to neurodegenerative diseases in Africa.The success of AI-BOND is anticipated to help build computational research capacities in Africa.

Indexed as

AfricaAlzheimer's disease and AD‐related dementiasbioinformaticsneurodegenerative diseasesonline trainingprograming

Identifiers

PMID39748840
PMCPMC11694528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.