Evidence map›Paper›PMID 39748835›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)

Application of the revised criteria for diagnosis and staging of Alzheimer's disease: Drug development and clinical practice.

Clifford R Jack, Ana Graf, Samantha C Burnham, Erin G Doty, Hans J Moebius, Philip Montenigro, Eric Siemers, Kaycee M Sink, Leslie M Shaw, Charlotte Thim Hansen and 4 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Mild cognitive impairment-to-Alzheimer's dementia progression risk: the contribution of the Interceptor project.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Implications and opportunities regarding biological frameworks in overt and prodromal dementia with Lewy bodies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Clifford R JackDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Ana GrafNovartis Pharma AG Basel Switzerland.
Samantha C BurnhamEli Lilly and Company Boston Massachusetts USA.
Erin G DotyEli Lilly and Company Indianapolis Indiana USA.
Hans J MoebiusAthira Pharma Inc. Bothell Washington USA.
Philip MontenigroEli Lilly and Company Boston Massachusetts USA.
Eric SiemersAcumen Pharmaceuticals Zionsville Indiana USA.
Kaycee M SinkGenentech Inc South San Francisco California USA.
Leslie M ShawDepartment of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.
Charlotte Thim HansenMedical & Science Novo Nordisk A/S Søborg Denmark.
Kristin R WildsmithNeurology Business Group Eisai Inc Nutley New Jersey USA.
Simin MahinradAlzheimer's Association Chicago Illinois USA.
Maria C CarrilloAlzheimer's Association Chicago Illinois USA.
Christopher J WeberAlzheimer's Association Chicago Illinois USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The newly proposed revised criteria for diagnosis and staging of Alzheimer's disease (AD) by the Alzheimer's Association (AA) Workgroup represent a significant milestone in the field. These criteria offer objective measures for diagnosing and staging biological AD, bridging the gap between research and clinical care. Although implementation feasibility may vary across regions and settings, improving the availability and accuracy of biomarkers, especially plasma biomarkers, is expected to enhance the applicability of these criteria in clinical practice. The Fall 2023 Alzheimer's Association Research Roundtable (AARR) meeting served as a forum for gathering industry perspectives and feedback on these revised criteria, ensuring that the new criteria inform research, clinical trial design, and clinical care. In this article, we outline a summary of the newly proposed "Revised Criteria for Diagnosis and Staging of AD: AA Workgroup" and provide highlights from the AARR meeting in fall 2023. Highlights: The Alzheimer's Association Research Roundtable (AARR) convened leaders from industry, academia, and government, to review the

Indexed as

Alzheimer's diseaseAlzheimer's disease biomarkersAlzheimer's disease diagnosisAlzheimer's disease imagingAlzheimer's disease stagingamyloid positron emission tomographybiofluid biomarkerspreclinical Alzheimer's disease–

Identifiers

PMID39748835
PMCPMC11694534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.