Evidence map›Paper›PMID 39748471›Full record

ArticleCancer2025

Cost and activity analysis for a citywide patient navigation intervention to engage underserved patients in breast cancer treatment: Findings from the Translating Research Into Practice study.

Serena Rajabiun, Howard J Cabral, Clara A Chen, Christine Lloyd-Travaglini, Julianne N Dugas, Deborah Amburgey, Madyson Fitzgerald, Stephenie C Lemon, Jennifer S Haas, Karen M Freund and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07474584 (The OpRESTORE AI-Patient Navigator Study), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07474584 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The OpRESTORE AI-Patient Navigator Study: Developing and Testing an AI-enhanced Patient Navigator for UK Veterans With Service-related Physical Health Problems

TypeinterventionalSponsorImperial College Healthcare NHS TrustRan2026 to 2028Enrolled1,389ConditionsVeteranArmsAI-OpRESTORE healthcare navigator, OpRESTORE healthcare navigation
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Serena RajabiunDepartment of Public Health, University of Massachusetts, Lowell, Massachusetts, USA.ORCID https://orcid.org/0000-0001-8770-5764
Howard J CabralBoston University School of Public Health, Boston, Massachusetts, USA.
Clara A ChenBoston University School of Public Health, Boston, Massachusetts, USA.
Christine Lloyd-TravagliniBoston University School of Public Health, Boston, Massachusetts, USA.
Julianne N DugasBoston University School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-1644-0134
Deborah AmburgeyBoston Medical Center, Boston, Massachusetts, USA.
Madyson FitzgeraldBoston Medical Center, Boston, Massachusetts, USA.
Stephenie C LemonUniversity of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.ORCID https://orcid.org/0000-0003-3321-6070
Jennifer S HaasMassachusetts General Hospital, Boston, Massachusetts, USA.
Karen M FreundTufts Medical Center, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-9049-5574
Tracy BattagliaBoston Medical Center, Boston, Massachusetts, USA.
TRIP Consortium

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Tufts Clinical and Translational Science Institute (Pilot Supplement)UL1TR002544 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2018 to 2022
$50.2M
University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
Harvard Clinical and Translational Science Center (UL1)UL1TR000170 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2012 to 2013
$31.4M
Translating Research Into Practice: A Regional Collaborative to Reduce Disparities in Breast Cancer CareU01TR002070 · NCATS · BOSTON MEDICAL CENTER · PI BATTAGLIA, TRACY ANN, FREUND, KAREN · 2017 to 2021
$8.7M
American Cancer Society CRP-17-112-06-COUNAmerican Cancer Society CRP-22-080-01-CTPSCenter for Clinical and Translational Science, University of Massachusetts UL1TR001453Clinical and Translational Science Institute, Boston University UL1TR001430Harvard Clinical and Translational Science Center UL1TR000170National Center for Advancing Translational Sciences National Institutes of Health U01TR002070NCATS NIH HHS U01 TR002070NCATS NIH HHS UL1 TR000170NCATS NIH HHS UL1 TR001430NCATS NIH HHS UL1 TR001453NCATS NIH HHS UL1 TR002544Tufts Clinical and Translational Science Institute UL1TR002544
6 · The paper itself

Abstract

backgroundPatient navigation is an evidence-based intervention for reducing delays in cancer care for underserved populations. There are limited economic evaluations of patient navigation in the US health care system and few have considered costs at various phases along the implementation spectrum. Having economic data, including costs and cost savings, can support sustainability of patient navigation programs. This study presents findings from a cost and activity analysis of a citywide hospital-based patient navigation program to engage women in timely breast cancer treatment post-diagnosis.

methodsThis study was conducted as part of Translating Research Into Practice (TRIP), a citywide patient navigation hybrid effectiveness-implementation research study conducted at five cancer care hospitals in Boston, Massachusetts. The authors surveyed participating patient navigators and supervisors about their tasks and level of effort over consecutive 10-day periods from 2019 to 2021. Patient navigators documented the time spent on activities in accordance with an 11-step protocol across five sites. Cost data were collected from annual fiscal year end expenditure hospital administrative databases at concurrent time frames. Descriptive analyses were used to calculate average time on tasks, cost per activity and cost per outcome. Cost savings were estimated by calculating the additional persons engaged in timely entry to treatment compared to a matched control group with respect to hospitalization and emergency room costs averted.

resultsAverage time spent per day on TRIP-specific navigation activities was approximately 3 hours (range, 0-8 hours) and the average time per patient per day was 25 minutes (n = 7 navigators). Total costs for clinical site interventions were $218,394 for startup and $392,407 for maintenance costs over the study period. A total of 223 patients were served during the intervention period with an average cost per patient of $979 for startup and $1759 for maintenance. Potential costs savings with the TRIP navigation program from averted hospitalization and emergency room visits for 63 additional patients who received timely treatment is estimated at $21,798-$30,429 and $2536-$5692 per patient, respectively, compared to treatment as usual.

conclusionsThe economic evaluation in this study provides insight into startup and implementation costs for uptake and scalability of navigation programs across a citywide system. The information may be useful for payors in reimbursing navigation activities and health systems in planning for high quality navigation programs to ensure patient-centered and timely treatment for women diagnosed with breast cancer.

Indexed as

Breast NeoplasmsPatient NavigationBostonFemaleHumansTranslational Research, BiomedicalVulnerable Populationsbreast cancercostcost savingspatient navigation

Identifiers

PMID39748471
PMCPMC11695749

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.