Evidence map›Paper›PMID 39748126›Full record

ArticleNPJ digital medicine2025

A real world evaluation of an innovative artificial intelligence tool for population-level breast cancer screening.

Karthik Adapa, Ashu Gupta, Sandeep Singh, Hitinder Kaur, Abhinav Trikha, Ajoy Sharma, Kumar Rahul

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karthik AdapaDepartment of Health and Family Welfare, Government of Punjab, Chandigarh, India. adapak@who.int.ORCID http://orcid.org/0000-0002-3970-588X
Ashu GuptaDepartment of Health and Family Welfare, Government of Punjab, Chandigarh, India.
Sandeep SinghDepartment of Health and Family Welfare, Government of Punjab, Chandigarh, India.
Hitinder KaurDepartment of Health and Family Welfare, Government of Punjab, Chandigarh, India.
Abhinav TrikhaDepartment of Health and Family Welfare, Government of Punjab, Chandigarh, India.
Ajoy SharmaDepartment of Health and Family Welfare, Government of Punjab, Chandigarh, India.
Kumar RahulDepartment of Health and Family Welfare, Government of Punjab, Chandigarh, India.

Funding

World Health Organization 001
6 · The paper itself

Abstract

In resource-constrained countries like India, mammography-based breast screening is challenging to implement. This state-wide study, funded by the Government of Punjab, evaluated the use of Thermalytix, a low-cost, radiation-free AI tool, for breast cancer screening. Community health workers, trained to raise awareness, mobilized women aged 30 and above for screening. Thermalytix triaged women into five risk categories based on thermal images, with high-risk women recalled for diagnostic imaging. Over 18 months, 15,069 women were screened across 183 locations in Punjab. The median age was 41 years, and 69.9% were asymptomatic. Of 460 women testing positive (recall rate 3.1%), 268 underwent follow-up imaging, and 27 were confirmed with breast cancer, yielding a detection rate of 0.18%. The positive predictive value of biopsy performed was 81.81%, and the median diagnostic interval was 21 days, with therapy initiation within 30 days. The study demonstrates the potential of Thermalytix for effective population-level breast cancer screening in low-resource settings.

Identifiers

PMID39748126
PMCPMC11696541

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.