Evidence map›Paper›PMID 39747843›Full record

ArticleNature communications2025

Sticky organisms create underwater biological adhesives driven by interactions between EGF- and GlcNAc- containing polysaccharides.

Jimin Choi, Seunghyeon Lee, Yongjin Lee, Dong Soo Hwang

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jimin ChoiDivision of Environmental Science and Engineering, Pohang University of Science and Technology, Pohang, South Korea.ORCID 0000-0002-5313-6249
Seunghyeon LeeDivision of Environmental Science and Engineering, Pohang University of Science and Technology, Pohang, South Korea.ORCID 0000-0003-1443-7118
Yongjin LeeInstitute of Chemical Process, Seoul National University, Gwanak-gu, Seoul, Republic of Korea.ORCID 0000-0002-7573-5648
Dong Soo HwangDivision of Environmental Science and Engineering, Pohang University of Science and Technology, Pohang, South Korea. dshwang@postech.ac.kr.ORCID 0000-0002-2487-2255

Funding

National Research Foundation of Korea (NRF) 2022R1I1A1A01064177National Research Foundation of Korea (NRF) No.2022R1A2C2007874National Research Foundation of Korea (NRF) RS-2024-00340746
6 · The paper itself

Abstract

Marine and terrestrial organisms often utilise EGF/EGF-like domains in wet adhesives, yet their roles in adhesion remain unclear. Here, we investigate the Barbatia virescense byssal system and uncover an oxidation-independent, reversible, and robust adhesion mechanism where EGF/EGF-like domain tandem repetitions in adhesive proteins bind robustly to GlcNAc-based biopolymer. EGF/EGF-like-domain-containing proteins demonstrate over three-fold superior underwater adhesion to chitosan compared to the well-known strongest wet-adhesive proteins, mefp-5, and suckerin, when adhering to mica in an surface forces apparatus-based measurement. Additionally, as the degree of acetylation of chitosan decreases from 20.0 to 5.34%, the underwater adhesion energy between mefp-2 and chitosan decreases from |Wad | ≈ 41.80 to 12.92 ± 0.40 mJm

Indexed as

AcetylglucosamineChitosanEpidermal Growth FactorAdhesivesAnimalsPolysaccharidesProtein BindingAcetylglucosamineAdhesivesChitosanEpidermal Growth FactorPolysaccharides

Identifiers

PMID39747843
PMCPMC11697411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.