ArticleNature communications2025
Sticky organisms create underwater biological adhesives driven by interactions between EGF- and GlcNAc- containing polysaccharides.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Photothermal-Chemotherapeutic Microneedle Patch Coloaded with HMnOACS applied materials & interfaces · 2026Article
- Glycans in adhesion and fertilization: histochemical and ultrastructural insights from the chaetognath Spadella cephaloptera.Frontiers in zoology · 2026Article
- Post-translational modifications of silk proteins.RSC chemical biology · 2026Review
- Thermo-responsive, on-demand adhesive and tissue-conformal hydrogel electrodes for organ repair and brain-computer interfaces.Materials today. Bio · 2026Article
- Harnessing marine-derived materials for therapeutics innovations: Advances in biomaterials from the ocean.Materials today. Bio · 2025Review
- Amyloid-like Structures in Marine Adhesive Proteins.Marine drugs · 2025Review
- Reversible biobased adhesives enable closed-loop engineered composites.Nature communications · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Marine and terrestrial organisms often utilise EGF/EGF-like domains in wet adhesives, yet their roles in adhesion remain unclear. Here, we investigate the Barbatia virescense byssal system and uncover an oxidation-independent, reversible, and robust adhesion mechanism where EGF/EGF-like domain tandem repetitions in adhesive proteins bind robustly to GlcNAc-based biopolymer. EGF/EGF-like-domain-containing proteins demonstrate over three-fold superior underwater adhesion to chitosan compared to the well-known strongest wet-adhesive proteins, mefp-5, and suckerin, when adhering to mica in an surface forces apparatus-based measurement. Additionally, as the degree of acetylation of chitosan decreases from 20.0 to 5.34%, the underwater adhesion energy between mefp-2 and chitosan decreases from |Wad | ≈ 41.80 to 12.92 ± 0.40 mJm
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Registered trials
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