Evidence map›Paper›PMID 39747833›Full record

ArticleNature communications2025

Parameters for one health genomic surveillance of Escherichia coli from Australia.

Anne E Watt, Max L Cummins, Celeste M Donato, Wytamma Wirth, Ashleigh F Porter, Patiyan Andersson, Erica Donner, Australian Pathogen Genomics One Health Working Group, Amy V Jennison, Torsten Seemann and 2 more

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Global genomic landscape of theNew microbes and new infections · 2026
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  3. Article
  4. Article
  5. A community-based One Health approach to the pandemic dynamics ofAntimicrobial agents and chemotherapy · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Detection of amoxicillin-resistant and multidrug-resistantMicrobiology (Reading, England) · 2026
    Article
  10. Integrated study on the occurrence and genomic features ofApplied and environmental microbiology · 2026
    Article
  11. Genomic Epidemiology of ESBL and Non-ESBL-ProducingAntibiotics (Basel, Switzerland) · 2026
    Article
  12. Cross-sectoral sharing of CTX-M-producingMicrobiology spectrum · 2026
    Article
  13. TheMicrobial genomics · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Anne E Watt *Microbiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-3842-0479
Max L Cummins *Australian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, New South Wales, Australia.ORCID 0000-0001-9333-7160
Celeste M Donato *Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Wytamma WirthDepartment of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Ashleigh F PorterDepartment of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-5705-5796
Patiyan AnderssonMicrobiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Erica DonnerFuture Industries Institute, University of South Australia, Mawson Lakes, South Australia, Australia.
Australian Pathogen Genomics One Health Working Group
Amy V JennisonPublic Health Microbiology, Public and Environmental Health, Pathology Queensland, Queensland Department of Health, Brisbane, Queensland, Australia.
Torsten SeemannMicrobiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-6046-610X
Steven P DjordjevicAustralian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, New South Wales, Australia. steven.djordjevic@uts.edu.au.ORCID 0000-0001-9301-5372
Benjamin P HowdenMicrobiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia. bhowden@unimelb.edu.au.ORCID 0000-0003-0237-1473

Funding

Department of Health | National Health and Medical Research Council (NHMRC) GNT1196103
6 · The paper itself

Abstract

Genomics is a cornerstone of modern pathogen epidemiology yet demonstrating transmission in a One Health context is challenging, as strains circulate and evolve within and between diverse hosts and environments. To identify phylogenetic linkages and better define relevant measures of genomic relatedness in a One Health context, we collated 5471 Escherichia coli genome sequences from Australia originating from humans (n = 2996), wild animals (n = 870), livestock (n = 649), companion animals (n = 375), environmental sources (n = 292) and food (n = 289) spanning over 36 years. Of the 827 multi-locus sequence types (STs) identified, 10 STs were commonly associated with cross-source genomic clusters, including the highly clonal ST131, pandemic zoonotic lineages such as ST95, and emerging human ExPEC ST1193. Here, we show that assessing genomic relationships at ≤ 100 SNP threshold enabled detection of cross-source linkage otherwise obscured when applying typical outbreak-oriented relatedness thresholds ( ≤ 20 SNPs) and should be considered in interrogation of One Health genomic datasets.

Indexed as

Escherichia coliEscherichia coli InfectionsGenome, BacterialGenomicsOne HealthPhylogenyPolymorphism, Single NucleotideAnimalsAnimals, WildAustraliaDisease OutbreaksHumansLivestockMultilocus Sequence Typing

Identifiers

PMID39747833
PMCPMC11696363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.