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ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2025

Controversies in the use of next-generation imaging for evaluation and treatment decision-making in patients with prostate cancer after biochemical recurrence: views from a Spanish expert panel.

Xavier Maldonado, Anna Boladeras, José María Gaya, Jesús Muñoz, Jacques Planas, Gemma Sancho, José Francisco Suárez

Abstract readReview
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In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xavier MaldonadoRadiation Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain. xavier.maldonado@vallhebron.cat.ORCID http://orcid.org/0000-0003-2045-4723
Anna BoladerasRadiation Oncology Department, Institut Català d'Oncologia. L'Hospitalet del Llobregat University Hospital, Barcelona, Spain.
José María GayaUrology Department, Fundació Puigvert University Hospital, Barcelona, Spain.
Jesús MuñozUrology Department, Consorci Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain.
Jacques PlanasUrology Department, Barcelona Vall d'Hebron University Hospital, Barcelona, Spain.
Gemma SanchoRadiation Oncology Department, Hospital Universitari de La Santa Creu I Sant Pau, Barcelona, Spain.
José Francisco SuárezUrology Department, Hospital Universitari de Bellvitge, L'Hospitalet del Llobregat, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiagnosing and managing biochemical recurrence (BCR) of prostate cancer (PCa) following primary radical treatment remain a challenge. Implementing next-generation imaging (NGI) techniques has improved metastases detection. However, access to these techniques is heterogeneous, and controversies surround their use and subsequent treatment decisions. In November 2023, a multidisciplinary expert meeting was organized to discuss these aspects. This information was further reviewed in November 2024. AREAS COVERED: NGI-specific tracers' selection, evidence supporting patient selection for NGI after BRC, current treatment strategies in patients with BRC, and the role of NGIs in current and future therapeutic approaches. EXPERT OPINION: Despite improved detection performance compared to conventional imaging techniques, the application of NGIs to treatment decision-making and the impact on patient outcomes are yet to be proven. Given the lack of guidance, opinions and recommendations from multidisciplinary expert panels are valuable for diagnosing and adequately treating patients with BRC after radical treatment.

Indexed as

Clinical Decision-MakingNeoplasm Recurrence, LocalProstatic NeoplasmsDecision MakingHumansMaleProstate-Specific AntigenProstate-Specific AntigenBiochemical recurrenceDiagnosisManagementNext-generation imagingProstate-specific membrane antigenProstatic neoplasm

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.