Evidence map›Paper›PMID 39747799›Full record

ArticleMolecular diversity2025

Design, synthesis, biological evaluation and molecular docking of novel isatin-oxime ether derivatives as potential IDH1 inhibitors.

Kangning Wei, Kaige Guo, Ye Tao, Xuanming Gong, Guobing Yan, Liangliang Wang, Ming Guo

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular diversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kangning WeiCollege of Chemistry and Materials Engineering, Zhejiang A&F University, Hangzhou, 311300, China.
Kaige GuoCollege of Jiyang, Zhejiang A&F University, Zhuji, 311800, China.
Ye TaoCollege of Jiyang, Zhejiang A&F University, Zhuji, 311800, China.
Xuanming GongCollege of Jiyang, Zhejiang A&F University, Zhuji, 311800, China.
Guobing YanCollege of Jiyang, Zhejiang A&F University, Zhuji, 311800, China. gbyan@zafu.edu.cn.
Liangliang WangDepartment of Biology, Lishui University, Lishui, 323000, China.
Ming GuoCollege of Chemistry and Materials Engineering, Zhejiang A&F University, Hangzhou, 311300, China.

Funding

the Project Sponsored of Advanced Talents by Zhejiang A&F University 04251700031Zhejiang University Student Science and Technology Innovation Activity Plan 2024R412B039
6 · The paper itself

Abstract

A series of novel isatin-oxime ether derivatives were designed, synthesized and characterized by

Indexed as

Drug DesignIsatinIsocitrate DehydrogenaseOximesCell Line, TumorDrug Screening Assays, AntitumorEnzyme InhibitorsHumansMolecular Docking SimulationMolecular StructureEnzyme InhibitorsIDH1 protein, humanIsatinIsocitrate DehydrogenaseOximesAnticancer activityIsatinIsocitrate dehydrogenase 1Molecular dockingOxime ether

Identifiers

PMID39747799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.