Evidence map›Paper›PMID 39747631›Full record

ArticleScientific reports2025

Prevalence and risk factors of long COVID-19 persisting for 2 years in Hainan Province: a population-based prospective study.

Daya Zhang, Chen Chen, Yunqian Xie, Shuo Zhou, Da Li, Fan Zeng, Shimei Huang, Yanting Lv, Xianfeng Huang, Fengjiao Mao and 10 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Daya Zhang *The Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.ORCID 0000-0001-6133-8919
Chen Chen *The Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Yunqian Xie *Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Yehai Avenue, #368, Longhua District, Haikou, 570216, Hainan Province, China.
Shuo ZhouThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Da LiThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Fan ZengThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Shimei HuangThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Yanting LvThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Xianfeng HuangThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Fengjiao MaoThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Jinglei KuangThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Jin GanThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Xiaojing XuThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Shiju ChenThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Runxiang ChenThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Xiaodong ZhangThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Sangni XuThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Minyu ZengThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Haoyue RenThe Second School of Clinical Medicine, Hainan Medical University, Haikou, 571199, China.
Feihu BaiDepartment of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Yehai Avenue, #368, Longhua District, Haikou, 570216, Hainan Province, China. baifeihu_hy@163.com.ORCID 0000-0002-1560-6131

Funding

Hainan Province Education Reform Project hnjg2024-67Hainan Provincial Postgraduate Innovation Research Project Qhyb2022-133Joint Project on Health Science and Technology Innovation in Hainan Province WSJK2024MS150National Clinical Key Speciality Capacity Building Project 202330The specific research fund of The Innovation Platform for Academicians of Hainan Province YSPTZX202313
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) can lead to persistent symptoms, sequelae, and other medical complications that may last for weeks or months after recovery. The aim of the study is to assess the prevalence and risk factors of long COVID-19 persisting for 2 years in Hainan Province, China, to aid in its recognition, prevention, and treatment. Between July and August 2022, 960 individuals with confirmed SARS-CoV-2 infection in Hainan, China, were recruited. An epidemiological questionnaire was conducted via phone interviews to assess participants' recovery status after 2 years. Among the participants, 120 patients (12.5%) experienced at least one long COVID-19 complication. The most common symptoms were cough (33.3%, 40/120), followed by fatigue (25.9%, 31/120), hair loss (23.3%, 28/120), and dizziness (20.8%, 25/120). Independent risk factors included age over 65, moderate to severe infection, chronic diseases, irregular diet, late sleeping, anxiety, and fewer than 2 vaccinations (p < 0.05). While most individuals infected with COVID-19 fully recover, approximately 12.5% experience intermediate or long-term effects. This study is the first to identify the incidence and associated risk factors of long COVID-19 with the longest follow-up time, providing valuable insights for the timely restoration of pre-COVID-19 health.

Indexed as

COVID-19SARS-CoV-2AdultAgedChinaCoughDizzinessFatigueFemaleHumansMaleMiddle AgedPrevalenceProspective StudiesRisk FactorsYoung AdultCoronavirus disease 2019 (COVID-19)Initial recoveryLong COVID-19PrevalenceRisk factors

Identifiers

PMID39747631
PMCPMC11696313

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.