Evidence map›Paper›PMID 39747620›Full record

ArticleScientific reports2025

Development of nanofiber facial mask inspired by the multi-function of dried ginger (Zingiberis Rhizoma) essential oil.

Yiwen Hao, Xia Lin, Wenwen Liu, Tinghongyang Jiang, Xing Zhang, Shasha Yang, You Huang, Wenjing Lai, Chaomei Fu, Zhen Zhang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Research Status and Prospects ofGastroenterology research and practice · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yiwen Hao *School of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xia Lin *School of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Wenwen LiuSchool of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Tinghongyang JiangSchool of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xing ZhangSchool of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Shasha YangSchool of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
You HuangSchool of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Wenjing LaiChengdu Institute of Food Inspection, Chengdu, China. 838708151@qq.com.
Chaomei FuSchool of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China. chaomeifu@126.com.
Zhen ZhangSchool of Pharmacy, School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China. zhangzhendr@126.com.

Funding

Chengdu University of Traditional Chinese Medicine Xinglin scholars Qingji talent project No. QJRC2022027the fellowship from China Scholarship Council No. 202308510149the Science and technology research project of Sichuan Administration of Traditional Chinese Medicine No. 2023MS600
6 · The paper itself

Abstract

Plant extracts, especially herbal extracts, are in line with the cosmetics development trend of natural and safe in today's world. Dried ginger essential oil (DGEO) is a fragrant oily liquid extracted from the dried roots of Zingiber officinale Rosc. This research investigated DGEO could effectively inhibit Staphylococcus aureus and Propionibacterium acnes. And delay skin aging in mice by down-regulating the expression of TNF-α and the production of MMP-1. These indicates that DGEO has antibacterial and anti-aging effects, and has the potential in beauty and skin care. However, DGEO is easy to volatilize, so it is lack of stability, and the application of DGEO is greatly limited. Therefore, we aim to improve the stability of DGEO and expand its application in facial mask. To achieve this, DGEO was firstly complexed with the β-cyclodextrin (β-CD) to prepare DGEO-β-CD-IC. Then, electrospinning was used to make DGEO-βCD-IC into a nanofiber facial mask. In this process, we found that the thermal stability of DGEO-βCD-IC was significantly improved, and the degradation process was slower than that of physical mixture. During the preparation of the nanofiber mask, DGEO did not undergo a chemical reaction. And the fibers of facial mask were evenly distributed, with smooth surfaces and tight structures. Its diameter was between 90 and 110 nm. And the facial mask had good hydrophilic performance and moisturizing efficacy. It could increase the skin water content by 47.82% on average. What's more, the safety tests showed that the facial mask was mild and safe. These results show that we improve the stability of DGEO and successfully develop a promising application prospects nanofiber mask. This work may enrich the use of herbal extracts in skincare products.

Indexed as

NanofibersOils, VolatilePropionibacterium acnesSkin AgingStaphylococcus aureusZingiber officinaleAnimalsAnti-Bacterial Agentsbeta-CyclodextrinsHumansMicePlant ExtractsAnti-Bacterial Agentsbeta-CyclodextrinsbetadexOils, VolatilePlant ExtractsDried ginger essential oilElectrospinningNanofiber facial maskβ-cyclodextrin

Identifiers

PMID39747620
PMCPMC11697445

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.