Evidence map›Paper›PMID 39747535›Full record

ArticleScientific reports2025

Probiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomes.

Rungdawan Wongsamart, Naraporn Somboonna, Thanya Cheibchalard, Piriya Klankeo, Jakavat Ruampatana, Morakot Nuntapaitoon

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Winning the battle of intestinal peace withFrontiers in microbiology · 2025
    Review
  11. Article
  12. MaternalComputational and structural biotechnology journal · 2025
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rungdawan WongsamartDepartment of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Naraporn SomboonnaDepartment of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand. Naraporn.S@chula.ac.th.
Thanya CheibchalardDepartment of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Piriya KlankeoOmics Sciences and Bioinformatics Center, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Jakavat RuampatanaDepartment of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand.
Morakot NuntapaitoonMulti-Omics for Functional Products in Food, Cosmetics and Animals Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand. Morakot.N@chula.ac.th.

Funding

Ratchadapisek Sompoch Endowment Fund 2021 764002-DTThailand Research Fund, Thailand Science Research and Innovation Fund Chulalongkorn University CU_FRB65_hea(68)_131_23_61Thailand Research Fund, Thailand Science Research and Innovation Fund Chulalongkorn University FOOD_FF_68_013_3100_003the Second Century Fund (C2F)
6 · The paper itself

Abstract

Maintaining a diverse and balanced sow milk microbiome is essential to piglet development. Thus, this study aimed to examine the effects of probiotic Bacillus licheniformis supplementation on the microbiome composition of sow colostrum and milk, and to review associated health findings in piglets. B. licheniformis DSMZ 28710 was supplemented at 10 g/day as feed additive before predicted farrowing until weaning by top dressing. Colostrum and milk samples were collected for metagenomic DNA extraction, 16s rRNA sequencing, and bioinformatics analyses for bacterial microbiota diversity. Results indicated that the supplementation increased the abundances of beneficial bacteria, such as Lactobacillus, Pediococcus, Bacteroides, and Bifidobacterium, while decreasing the abundances of pathogenic bacteria, such as Staphylococcus aureus, Enterobacteriaceae, and Campylobacter in the colostrum. The supplementation increased diversity while maintaining richness and evenness. Moreover, the rise in predicted microbial community metabolic function in membrane transport pathways provides crucial evidence showing that the supplementation is potentially beneficial to piglets, as these pathways are important for providing nutrients and immunity to offspring. This research highlights the importance of microbiome composition in sow milk and the potential of B. licheniformis supplementation as a means to improve piglet health and development.

Indexed as

Bacillus licheniformisMicrobiotaMilkProbioticsAnimal FeedAnimalsColostrumDietary SupplementsFemaleRNA, Ribosomal, 16SSwineRNA, Ribosomal, 16SBacillus licheniformisGestation and lactationMicrobiomeProbioticsSow milk

Identifiers

PMID39747535
PMCPMC11696930

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.