Evidence map›Paper›PMID 39747477›Full record

ArticleScientific reports2025

AI-based visualization of loose connective tissue as a dissectable layer in gastrointestinal surgery.

Yuta Kumazu, Nao Kobayashi, Seigo Senya, Yuya Negishi, Kazuya Kinoshita, Yudai Fukui, Kazuhito Mita, Tomohiko Osaragi, Toshihiro Misumi, Hisashi Shinohara

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Artificial intelligence-based anatomical recognition improves surgeon decision-making during robotic gastrectomy.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuta Kumazu *Anaut Inc., 2-1-6-19F WeWork Hibiya Park Front, Uchisaiwaicho, Chiyodaku, Tokyo, 100-0011, Japan. kumazu.y@anaut-surg.com.
Nao Kobayashi *Anaut Inc., 2-1-6-19F WeWork Hibiya Park Front, Uchisaiwaicho, Chiyodaku, Tokyo, 100-0011, Japan.
Seigo SenyaAnaut Inc., 2-1-6-19F WeWork Hibiya Park Front, Uchisaiwaicho, Chiyodaku, Tokyo, 100-0011, Japan.
Yuya NegishiAnaut Inc., 2-1-6-19F WeWork Hibiya Park Front, Uchisaiwaicho, Chiyodaku, Tokyo, 100-0011, Japan.
Kazuya KinoshitaDepartment of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yudai FukuiDepartment of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan.
Kazuhito MitaDepartment of Surgery, Tsudanuma Central General Hospital, Chiba, Japan.
Tomohiko OsaragiDepartment of Surgery, Hadano Red Cross Hospital, Kanagawa, Japan.
Toshihiro MisumiDepartment of Data Science, National Cancer Center Hospital East, Chiba, Japan.
Hisashi ShinoharaDepartment of Gastroenterological Surgery, Hyogo Medical University, Hyogo, Japan.

Funding

Japan Society for the Promotion of Science 22H03153Japan Society for the Promotion of Science KAKENHI 19H03735Japan Society for the Promotion of Science KAKENHI 20K08997
6 · The paper itself

Abstract

We aimed to develop an AI model that recognizes and displays loose connective tissue as a dissectable layer in real-time during gastrointestinal surgery and to evaluate its performance, including feasibility for clinical application. Training data were created under the supervision of gastrointestinal surgeons. Test images and videos were randomly sampled and model performance was evaluated visually by 10 external gastrointestinal surgeons. The mean Dice coefficient of the 50 images was 0.46. The AI model could detect at least 75% of the loose connective tissue in 91.8% of the images (459/500 responses). False positives were found for 52.6% of the images, but most were not judged significant enough to affect surgical judgment. When comparing the surgeon's annotation with the AI prediction image, 5 surgeons judged the AI image was closer to their own recognition. When viewing the AI video and raw video side-by-side, surgeons judged that in 99% of the AI videos, visualization was improved and stress levels were acceptable when viewing the AI prediction display. The AI model developed demonstrated performance at a level approaching that of a gastrointestinal surgeon. Such visualization of a safe dissectable layer may help to reduce intraoperative recognition errors and surgical complications.

Indexed as

Connective TissueDigestive System Surgical ProceduresArtificial IntelligenceHumansSurgeonsVideo RecordingAIColorectal surgeryDissectable layerGastrectomyInguinal hernia repairLoose connective tissue

Identifiers

PMID39747477
PMCPMC11695969

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.