Evidence map›Paper›PMID 39747417›Full record

ReviewAesthetic plastic surgery2025

Complications of Nonsurgical Rhinoplasty with Hyaluronic Acid Injections: A Narrative Review.

Alberto Caranti, Radulesco Thomas, Fabio Facchini, Ruggero Campisi, Chiara Bianchini, Stefano Pelucchi, Andrea Ciorba, Gianicola Iannella, Antonino Maniaci, Justin Michel and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alberto CarantiPrimus Medical Center (GVM), Gruppo Otorinolaringoiatrico della Romagna, Via Punta di Ferro 2/c, 47122, Forlì, FC, Italy. dott.albertocaranti@gmail.com.
Radulesco ThomasAix-Marseille University, APHM, IUSTI, La Conception University Hospital, Department of Oto-Rhino-Laryngology Head and Neck Surgery, Marseille, France.
Fabio FacchiniOtorhinolaryngology and Audiology Unit, Department of Neurosciences and Rehabilitation, University of Study of Ferrara, via Aldo Moro 8, 44124, Ferrara, FE, Italy.
Ruggero CampisiPrimus Medical Center (GVM), Gruppo Otorinolaringoiatrico della Romagna, Via Punta di Ferro 2/c, 47122, Forlì, FC, Italy.
Chiara BianchiniOtorhinolaryngology and Audiology Unit, Department of Neurosciences and Rehabilitation, University of Study of Ferrara, via Aldo Moro 8, 44124, Ferrara, FE, Italy.
Stefano PelucchiOtorhinolaryngology and Audiology Unit, Department of Neurosciences and Rehabilitation, University of Study of Ferrara, via Aldo Moro 8, 44124, Ferrara, FE, Italy.
Andrea CiorbaOtorhinolaryngology and Audiology Unit, Department of Neurosciences and Rehabilitation, University of Study of Ferrara, via Aldo Moro 8, 44124, Ferrara, FE, Italy.
Gianicola IannellaOtorhinolaryngology Department, Sapienza University of Rome, Rome, Italy.
Antonino ManiaciFaculty of Medicine and Surgery, University of Enna Kore, 94100, Enna, Italy.
Justin MichelAix-Marseille University, APHM, IUSTI, La Conception University Hospital, Department of Oto-Rhino-Laryngology Head and Neck Surgery, Marseille, France.
Claudio ViciniPrimus Medical Center (GVM), Gruppo Otorinolaringoiatrico della Romagna, Via Punta di Ferro 2/c, 47122, Forlì, FC, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increasing popularity of cosmetic procedures has led to a rise in both surgical and nonsurgical interventions. Rhinoplasty, particularly nonsurgical rhinoplasty using injectable fillers such as hyaluronic acid (HA), has become highly sought after due to its minimally invasive nature. Despite its benefits, complications can occur, ranging from minor to severe.

methodsThis narrative review adheres to PRISMA guidelines and evaluates the complications associated with injectable rhinofillers. A comprehensive search was conducted in PubMed and Embase databases for articles published between January 1, 1990, and September 30, 2023, using specific keywords related to nonsurgical rhinoplasty and its complications. A total of 180 articles were identified, with 80 included in the final review.

resultsComplications from injectable rhinofillers vary widely. Common early-onset issues include asymmetry, injection site reactions, and hypersensitivity. Severe complications like vascular occlusion can lead to tissue ischemia, necrosis, or even blindness. Infection, Tyndall effect, nodules, granulomas, scarring, and biofilms are also documented. The incidence of severe complications is relatively low but requires immediate and effective management to prevent long-term consequences.

conclusionsNonsurgical rhinoplasty using fillers, particularly HA, is generally safe with a low risk of severe complications. Awareness and prompt management of potential complications are crucial for practitioners. Preventative measures, precise techniques, and thorough anatomical knowledge can mitigate risks, ensuring better patient outcomes. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Indexed as

Dermal FillersHyaluronic AcidRhinoplastyHumansInjection Site ReactionDermal FillersHyaluronic AcidHyaluronic acidInjectable rhino fillerNon-surgical rhinoplastyRhino fillers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.