Evidence map›Paper›PMID 39747403›Full record

ArticleScientific reports2025

In silico analysis of mitochondrial DNA genes: implication for conservation of Tor putitora (Hamilton, 1822).

Kushal Thakur, Deepika Sharma, Ankita Sharma, Amit Kumar Sharma, Danish Mahajan, Bhavna Brar, Hishani Kumari, Sandeep Kumar, Madhu Bala, Sunil Kumar and 1 more

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Kushal ThakurDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.ORCID 0000-0003-3801-4531
Deepika SharmaDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.
Ankita SharmaDr. Ambedkar Centre of Excellence, Central University of Himachal Pradesh, 176206, Dharamsala, India.ORCID 0000-0003-1360-5810
Amit Kumar SharmaDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.ORCID 0000-0002-1382-4290
Danish MahajanDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.ORCID 0000-0001-5953-5876
Bhavna BrarDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.
Hishani KumariDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.ORCID 0009-0000-1963-7958
Sandeep KumarDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.ORCID 0000-0001-7142-0852
Madhu BalaDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.ORCID 0009-0007-2715-7402
Sunil KumarDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India.ORCID 0000-0003-1152-3037
Rakesh KumarDepartment of Animal Sciences, Central University of Himachal Pradesh, 176206, Dharamsala, India. drthakurcuhp@hpcu.ac.in.ORCID 0000-0003-0376-2273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tor putitora is an endangered cyprinid fish constrained to cold water and is also considered an indicator of a healthy aquatic ecosystem. The present study aimed to examine the haplotypic diversity, genetic variation and population structure of T. putitora isolates using COI and Cyt b gene sequences submitted in GenBank. Bioinformatic analysis was carried out using 106 COI and 183 Cyt b gene sequences as well as 2 reference genome sequences. Analysis of COI and Cyt b gene reveals 18 and 85 haplotypes respectively. Mutation was observed at 44 different sites in COI and 173 in Cyt b gene sequences. Haplotype 4 and haplotype 37 were considered ancestral in COI and Cyt b respectively. Analysis of COI gene reveals moderate haplotype diversity (0.630) and low Nucleotide diversity (0.00662) whereas Cyt b has higher haplotype diversity (0.804) and low Nucleotide diversity (0.00582). Moreover, the neutrality test such as Tajima's D, and Fu's Fs showed negative values in both gene sequences, suggesting population expansion attributed to habitat destruction. So, comprehending the genetic variability within and among the T. putitora population is crucial for conserving and managing this species. Integration of genetic diversity into conservation planning can enhance the effectiveness of breeding programs and habitat restoration efforts.

Indexed as

Conservation of Natural ResourcesCyprinidaeDNA, MitochondrialGenetic VariationHaplotypesAnimalsComputer SimulationCytochromes bElectron Transport Complex IVEndangered SpeciesPhylogenyCytochromes bDNA, MitochondrialElectron Transport Complex IVCOIConservationCyt bGenetic variationHaplotypeIn silico analysisTor putitora

Identifiers

PMID39747403
PMCPMC11696798

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