Evidence map›Paper›PMID 39747356›Full record

ArticleScientific reports2025

Genomic microsatellite characterization and development of polymorphic microsatellites in Eospalax baileyi.

Qiqi Hou, Weihong Ji, Kang An, Yuchen Tan, Penghui Liu, Junhu Su

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Qiqi HouKey Laboratory of Grassland Ecosystem (Ministry of Education), Pratacultural College, Gansu Agricultural University, Lanzhou, 730070, China.
Weihong JiFaculty of Science, University of Auckland, Auckland, New Zealand.
Kang AnKey Laboratory of Grassland Ecosystem (Ministry of Education), Pratacultural College, Gansu Agricultural University, Lanzhou, 730070, China.
Yuchen TanKey Laboratory of Grassland Ecosystem (Ministry of Education), Pratacultural College, Gansu Agricultural University, Lanzhou, 730070, China.
Penghui LiuKey Laboratory of Grassland Ecosystem (Ministry of Education), Pratacultural College, Gansu Agricultural University, Lanzhou, 730070, China.
Junhu SuKey Laboratory of Grassland Ecosystem (Ministry of Education), Pratacultural College, Gansu Agricultural University, Lanzhou, 730070, China. sujh@gsau.edu.cn.

Funding

High-end Foreign Experts Recruitment Plan of China G2022042008LNational Natural Science Foundation of China 32272566the Industrial Support Program Project of Gansu Provincial Education Department 2022CYZC-47the open competition projects to select the best candidates for leading key initiatives of the key laboratory of grassland ecosystems, Gansu Agricultural University, Ministry of Education KLGE-2024-02
6 · The paper itself

Abstract

Microsatellite markers are cost-effective, rapid, efficient, and show great advantages in in large-sample kinship analysis and population structure studies. However, microsatellite loci are seriously underdeveloped in non-model organisms. The plateau zokor (Eospalax baileyi) is a key species living underground in the Tibetan Plateau, the effective management of which has long been challenging. In this study, we analyzed the distribution characteristics and functions of microsatellites in the genome of plateau zokors, and their polymorphic sites. The mononucleotide and dinucleotide types being the most abundant in the genome. The largest number of microsatellites and their abundance in the intergenic region whereas the smallest number of microsatellites and their abundance in the coding region. The coding sequences containing microsatellites were annotated to 52 major functional genes and assigned 19,358 Gene Ontology entries. The Kyoto Encyclopedia of Genes and Genomes pathway was the most enriched in the signal transduction pathway. Thirteen pairs of polymorphic loci were successfully amplified, with the number of alleles ranging from 3 to 8, observed heterozygosity ranging from 0.059 to 0.810, and expected heterozygosity ranging from 0.469 to 0.854. These microsatellite markers provide a cornerstone for studies on the identification of parentage and population genetics of plateau zokors.

Indexed as

Microsatellite RepeatsPolymorphism, GeneticAllelesAnimalsGenetics, PopulationGenomicsGenome-wideMicrosatellitesPlateau zokorPolymorphism

Identifiers

PMID39747356
PMCPMC11696105

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