Evidence map›Paper›PMID 39747028›Full record

ArticleNature communications2025

A stable and biocompatible shortwave infrared nanoribbon for dual-channel in vivo imaging.

Cheng Yao, Ruwei Wei, Xiao Luo, Jie Zhou, Xiaodong Zhang, Xicun Lu, Yan Dong, Ruofan Chu, Yuxin Sun, Yu Wang and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Enhanced SWIR photodetection in TeScientific reports · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Cheng YaoState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0009-0002-8819-1085
Ruwei WeiState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Xiao LuoShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China.ORCID 0000-0002-2561-6114
Jie ZhouState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai, China.
Xiaodong ZhangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Xicun LuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Yan DongState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Ruofan ChuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Yuxin SunState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Yu WangShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China.ORCID 0009-0004-0940-7250
Wencheng XiaInterdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
Dahui QuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0000-0002-2039-3564
Cong LiuInterdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0003-3425-6672
Jun RenHubei Key Laboratory for Precision Synthesis of Small Molecule Pharmaceuticals & Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan, China.
Guangbo GeInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jinquan ChenState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai, China.ORCID 0000-0003-0652-1379
Xuhong QianState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Youjun YangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China. youjunyang@ecust.edu.cn.ORCID 0000-0001-7085-6048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The shortwave infrared (SWIR) region is an ideal spectral window for next-generation bioimaging to harness improved penetration and reduced phototoxicity. SWIR spectral activity may also be accessed via supramolecular dye aggregation. Unfortunately, development of dye aggregation remains challenging. We propose a crystal-aided aggregate synthesis (CAASH) approach to introduce a layer of rationality for the development of J-aggregate and the successful development of a water-soluble SWIR JV-aggregate with a bisbenzannulated silicon rhodamine scaffold (ESi5). The resulting SWIR-aggregates exhibit excellent stabilities toward organic solvents, pH, sonication, photobleaching, thiols, and endogenous oxidative species. Notably, the aggregates have a high structure-dependent melting temperature of ca. 330-335 K. In fact, the heating/annealing process can be exploited to reduce aggregation disorder. The aggregates are biocompatible and have broad potential in in vivo fluorescence and photoacoustic imaging and more.

Indexed as

Biocompatible MaterialsInfrared RaysAnimalsFluorescent DyesHumansMiceNanotubes, CarbonOptical ImagingPhotoacoustic TechniquesRhodaminesBiocompatible MaterialsFluorescent DyesNanotubes, CarbonRhodamines

Identifiers

PMID39747028
PMCPMC11696549

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.