ArticleNature communications2025
A soft thermal sensor for the continuous assessment of flow in vascular access.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Numerical Investigation of a Skin-Interfaced Thermal Sensor for Joint Estimation of Tissue Thermal Conductivity and Blood Velocity.Micromachines · 2026Article
- Chemical-Sensing Catheters for Long-Term and Personalized Therapeutic Management.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Clinical applicable skin-interfaced thermal guiding sensor for warning perioperative abnormalities in core body temperature and blood perfusion rate.Nature communications · 2026Article
- Materials-Structure-Hardware-Algorithm Co-Driven Hierarchical Optimization for Flexible Sensors.Nano-micro letters · 2026Review
- Reversible Thermoactuation Unlocks Minimally Invasive Implantation and Retrieval of Soft Bioelectronics.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Wireless, non-invasive, high-resolution thrill sensor for continuous vascular access monitoring of hemodialysis patients.Nature communications · 2026Article
- Deep learning-integrated multilayer thermal gradient sensing platform for real-time blood flow monitoring.Science advances · 2026Article
- Laser Micromachining for Bioelectronics: Past, Present, and Future.Small methods · 2026Review
- Digitized Acoustic Analysis for Monitoring Hemodialysis Access Dysfunction: Insights from Vascular Imaging and Post-Angioplasty Data.Journal of clinical medicine · 2026Article
- Hemodialysis vascular access flow surveillance: Current evidence and future directions.Journal of the Chinese Medical Association : JCMA · 2025Review
- A Deep-Learned Monolithic Nanoparticle Asymmetric Thermal Flow Sensor for Flow Vector Estimation.ACS nano · 2025Article
- Analysis of Personalized Cardiovascular Drug Therapy: From Monitoring Technologies to Data Integration and Future Perspectives.Biosensors · 2025Review
- Implantable Biosensors for Vascular Diseases: Directions for the Next Generation of Active Diagnostic and Therapeutic Medical Device Technologies.Biosensors · 2025Review
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Hemodialysis for chronic kidney disease (CKD) relies on vascular access (VA) devices, such as arteriovenous fistulas (AVF), grafts (AVG), or catheters, to maintain blood flow. Nonetheless, unpredictable progressive vascular stenosis due to neointimal formation or complete occlusion from acute thrombosis remains the primary cause of mature VA failure. Despite emergent surgical intervention efforts, the lack of a reliable early detection tool significantly reduces patient outcomes and survival rates. This study introduces a soft, wearable device that continuously monitors blood flow for early detection of VA failure. Using thermal anemometry, integrated sensors noninvasively measure flow changes in large vessels. Bench testing with AVF and AVG models shows agreement with finite element analysis (FEA) simulations, while human and preclinical swine trials demonstrate the device's sensitivity. Wireless adaptation could enable at-home monitoring, improving detection of VA-related complications and survival in CKD patients.
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Registered trials
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