ArticleIndian pacing and electrophysiology journal
The importance of inflammation in atrial fibrillation recurrence in patients with atrial fibrillation treated with Cryo balloon ablation.
Article in Indian pacing and electrophysiology journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The Immune System as a Proarrhythmic Mediator: A Novel Paradigm for the Development of New Antiarrhythmic Therapy.The Canadian journal of cardiology · 2026Review
- Review
- Differential biomarker responses of hemolysis, inflammation, and myocardial injury after pulsed-field pulmonary vein isolation: balloon-in-basket vs. circular catheter systems.Frontiers in cardiovascular medicine · 2026Article
- Biomarker response to balloon-in-basket pulsed field ablation: does posterior wall isolation matter?Frontiers in cardiovascular medicine · 2026Article
- Differential inflammatory and myocardial biomarker response after pulsed field ablation for atrial fibrillation using balloon-in-basket vs pentaspline catheters.Heart rhythm O2 · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIM/
backgroundAlthough atrial fibrillation is the most common rhythm problem, the results of treatment to restore sinus rhythm are still not satisfactory. Nearly half of patients undergoing ablation relapse within one year. Therefore, triggered activities may not be the only cause. Inflammation is quite common in AF. In this study, we investigated the effect of PIV, an inflammatory marker, on recurrence.
methodsA total of 157 patients who underwent ablation with cryo balloon were included in the study. One-year follow-up was evaluated for causes of recurrence.
resultsWhen the inflammatory parameters between the two groups are analyzed, CRP (5.9 [5.0-6.9] vs 9.7 [7.6-11.9], p < 0.001), NL ratio (2.8 [2.5-3.0] vs 6.4 [5.0-6.8], p < 0.001), SII2 (618.5 [557.1-679.9] vs 1798.9 [1305.8-2292.1], p < 0.001), PIV (355.9 [313.4-398.4] vs 1832 [1317.8-2347.1], p < 001) were significantly higher in the AF recurrence group. ROC analysis showed that PIV had the best sensitivity and specificity.
conclusionsInflammation has been found to be a cause of AF recurrence and PIV is one of the best markers for this.
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Registered trials
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