Evidence map›Paper›PMID 39746230›Full record

ArticleSocial science & medicine (1982)2025

Longitudinal associations between intersectional stigmas, antiretroviral therapy adherence, and viral load among women living with HIV using multidimensional latent transition item response analysis.

Andrea Norcini-Pala, Kristi L Stringer, Mirjam-Colette Kempf, Deborah Konkle-Parker, Tracey E Wilson, Phyllis C Tien, Gina Wingood, Torsten B Neilands, Mallory O Johnson, Sheri D Weiser and 4 more

Abstract read
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Article in Social science & medicine (1982), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

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0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Andrea Norcini-PalaDepartment of Community Health Sciences, School of Public Health, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA. Electronic address: andrea.norcinipala@downstate.edu.
Kristi L StringerCommunity and Public Health, Middle Tennessee State University, Murfreesboro, TN, USA.
Mirjam-Colette KempfSchools of Nursing, Public Health and Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Deborah Konkle-ParkerDivision of Infectious Diseases, School of Medicine and School of Nursing, University of Mississippi Medical Center, Jackson, MS, USA.
Tracey E WilsonDepartment of Community Health Sciences, School of Public Health, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA.
Phyllis C TienDepartment of Medicine, University of California, San Francisco and Medical Service, Department of Veteran Affairs Medical Center, San Francisco, CA, USA.
Gina WingoodDepartment of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York City, NY, USA.
Torsten B NeilandsDepartment of Medicine, University of California, San Francisco, CA, USA.
Mallory O JohnsonDepartment of Medicine, University of California, San Francisco, CA, USA.
Sheri D WeiserDepartment of Medicine, University of California, San Francisco, CA, USA.
Carmen H LogieFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Canada.
Elizabeth F TopperDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, USA.
Janet M TuranDepartment of Health Policy and Organization, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Bulent TuranDepartment of Psychology, Koc University, Istanbul, Turkey; Department of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1M
Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
SF Bay Area MACS/WIHS Combined Cohort StudyU01HL146242 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bradley E Aouizerat, Jennifer Cohen Price · 2019 to 2026
$36.3M
Sex differences in the role of multi-omicsin HIV-associated carotid artery atherosclerosisU01HL146193 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Stephen J Gange, Elizabeth Topper · 2019 to 2026
$35.8M
MACS/WIHS Combined Cohort Study Clinical Research SiteU01HL146241 · NHLBI · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Anandi Nayan Sheth · 2019 to 2026
$24.2M
UAB-MISS MACS/WIHS Combined Cohort StudyU01HL146192 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI James Benjamin Brock, MIRJAM-COLETTE KEMPF · 2019 to 2026
$23.9M
MWCCS: Brooklyn Clinical Research SiteU01HL146202 · NHLBI · SUNY DOWNSTATE MEDICAL CENTER · PI TRACEY ELIZABETH WILSON, Jessica Eve Yager · 2019 to 2026
$23.6M
Evaluation of Neurobiological Mechanisms Mediating the Effect of Immune Activation on Neurocognitive Impairment and the Role of Psychosocial Factors Among Women Living with HIVR01MH131177 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Andrea Norcini Pala, Pariya Fazeli Wheeler · 2022 to 2026
$3.3M
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherenceK01MH125724 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI NORCINI PALA, ANDREA · 2021 to 2025
$878k
NCATS NIH HHS UL1 TR000004NHLBI NIH HHS U01 HL146192NHLBI NIH HHS U01 HL146193NHLBI NIH HHS U01 HL146202NHLBI NIH HHS U01 HL146241NHLBI NIH HHS U01 HL146242NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI050409NIMH NIH HHS K01 MH125724NIMH NIH HHS R01 MH131177
6 · The paper itself

Abstract

backgroundIn the US, Women, especially Black and Latina women living in disadvantaged environments, are disproportionally affected by HIV. Women living with HIV (WLHIV) have higher rates of suboptimal antiretroviral therapy (ART) adherence, and detectable viral load (VL). Experiences of intersectional poverty, HIV, gender, and racial stigmas may increase the rates of detectable VL through suboptimal ART adherence.

aimsTo explore longitudinal associations between intersectional stigmas, ART adherence, and detectable VL using multidimensional latent transition item response analysis.

participantsWLHIV (N = 459) in the [masked] sub-study of the [masked], from sites in Birmingham, AL, Jackson, MS, Atlanta, GA, and San Francisco, CA. ASSESSMENT: Experienced poverty, HIV, gender, and racial stigma, self-report ART adherence, and VL were assessed at four yearly follow-ups between 2016 and 2020.

resultsWe identified five classes of WLHIV with different combinations of experienced intersectional stigmas. Longitudinally, WLHIV with higher levels of poverty, gender, and racial stigma had higher odds of suboptimal ART adherence (<90%) (OR = 3.59, p < 0.001) and detectable VL (OR = 2.08, p = 0.028) compared to WLHIV with lower/moderately low stigmas levels. WLHIV in the highest stigma classes had higher odds of detectable VL, independently of ART adherence (Class 3: OR = 1.38, p = 0.016; Class 5: OR = 1.31, p = 0.046). These findings underscore the compounded effects of intersectional stigmas on HIV treatment outcomes.

conclusionIntersecting experiences of HIV, racial, gender, and poverty stigmas can increase detectable VL risk through suboptimal ART adherence, although other mechanisms may also be involved. Recognizing the complexity of intersectional stigmas is essential for developing approaches to improve WLHIV's HIV treatment outcomes.

Indexed as

HIV InfectionsHIV Long-Term SurvivorsMedication AdherenceSocial StigmaViral LoadWomenAdultAnti-HIV AgentsBehavior Rating ScaleFemaleHumansLatent Class AnalysisLongitudinal StudiesMiddle AgedMultivariate AnalysisOdds RatioAnti-HIV Agents

Identifiers

PMID39746230
PMCPMC11892020

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.