Evidence map›Paper›PMID 39746198›Full record

ArticleAnnals of the American Thoracic Society2025

The Association between All-Cause Mortality and Obstructive Sleep Apnea in Adults: A U-Shaped Curve.

Mehrnaz Azarian, Amin Ramezani, Amir Sharafkhaneh, Arash Maghsoudi, Meir Kryger, Robert J Thomas, M Brandon Westover, Javad Razjouyan

Abstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Mortality in narcolepsy and other sleep clinic patients: a 25-year propensity-matched VA cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  4. Article
  5. Overall Mortality and Comorbidities in Obstructive Sleep Apnea in Poland.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  6. Observational
  7. Article
  8. Age matters: the differential impact of OSA on metabolic health by age group.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  9. Effect of age on the association of obstructive sleep apnea with metabolic syndrome among obese and nonobese adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mehrnaz AzarianCenter for Innovations in Quality, Effectiveness, and Safety and.ORCID 0009-0000-1555-678X
Amin RamezaniCenter for Innovations in Quality, Effectiveness, and Safety and.ORCID 0009-0002-7952-3009
Amir SharafkhanehPulmonary, Critical Care, and Sleep Medicine Section, Medical Care Line, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas.ORCID 0000-0002-7893-2946
Arash MaghsoudiCenter for Innovations in Quality, Effectiveness, and Safety and.ORCID 0000-0002-1883-0753
Meir KrygerPulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.ORCID 0009-0007-3799-8280
Robert J ThomasDivision of Pulmonary, Critical Care, and Sleep Medicine and.ORCID 0000-0002-5575-3953
M Brandon WestoverDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; and.ORCID 0000-0003-4803-312X
Javad RazjouyanCenter for Innovations in Quality, Effectiveness, and Safety and.ORCID 0000-0003-1157-159X

Funding

Data-Driven Sleep Biomarkers of Brain Health, Heart Health, and MortalityR01HL161253 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI CLIFFORD, GARI DAVID, MIGNOT, EMMANUEL J · 2022 to 2025
$8.3M
Prospective Validation of Neurophysiologic Outcome Prediction in Acute Brain InjuryR01NS126282 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Aaron F Struck, Michael Brandon Westover · 2023 to 2026
$2.9M
Big Data and Deep Learning for the Interictal-Ictal-Injury ContiuumR01NS107291 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI WESTOVER, MICHAEL BRANDON · 2018 to 2022
$2.8M
Establishing a Brain Health Index from the Sleep ElectroencephalogramRF1NS120947 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CASH, SYDNEY S, THOMAS, ROBERT JOSEPH · 2021 to 2021
$2.4M
Establishing a Brain Health IndexR01NS120947 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI CASH, SYDNEY S, THOMAS, ROBERT JOSEPH · 2024 to 2025
$1.6M
Using Large Electronic Health Records and Advanced Analytics to Develop Predictive Frailty Trajectories in Patients with Heart FailureK25HL152006 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI RAZJOUYAN, JAVAD · 2020 to 2024
$719k
Airborne Hazards and Burn Pits Center of Excellence FY2024-002Center for Innovations in Quality, Effectiveness, and Safety CIN 13-413NHLBI NIH HHS 1K25HL152006-01NHLBI NIH HHS K25 HL152006NHLBI NIH HHS R01 HL161253NINDS NIH HHS R01 NS107291NINDS NIH HHS R01 NS120947NINDS NIH HHS R01 NS126282NINDS NIH HHS RF1 NS120947
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Sleep Apnea, ObstructiveAdultAgedAge FactorsCause of DeathDatabases, FactualFemaleHumansLogistic ModelsMaleMiddle AgedOdds RatioPolysomnographyPropensity ScoreRisk FactorsSeverity of Illness IndexApnea–Hypopnea indexintermittent hypoxiamortalitynatural language processingsleep apnea

Identifiers

PMID39746198
PMCPMC12005042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.