Evidence map›Paper›PMID 39745645›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

In Vivo Clonal Analysis Using MADM with Spatiotemporal Specificity.

Yuwei Peng, Efan Wang, Zhongfu Shen, Song-Hai Shi, Jian Ma

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuwei Peng *IDG/McGovern Institute of Brain Research, Tsinghua University, Beijing, People's Republic of China.
Efan Wang *IDG/McGovern Institute of Brain Research, Tsinghua University, Beijing, People's Republic of China.
Zhongfu ShenIDG/McGovern Institute of Brain Research, Tsinghua University, Beijing, People's Republic of China.
Song-Hai ShiIDG/McGovern Institute of Brain Research, Tsinghua University, Beijing, People's Republic of China. shisonghai@mail.tsinghua.edu.cn.
Jian MaIDG/McGovern Institute of Brain Research, Tsinghua University, Beijing, People's Republic of China. majian0509@mail.tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosaic analysis with double markers (MADM) is a powerful in vivo lineage tracing technique. It utilizes Cre recombinase-dependent interchromosomal recombination to restore the stable expression of two fluorescent proteins sparsely in individual dividing stem or progenitor cells and their progenies. Here, we describe the application of this technique for quantitative lineage analysis of radial glial progenitors in the developing mouse neocortex at the single-cell resolution.

Indexed as

Cell LineageIntegrasesAnimalsEpendymoglial CellsMiceMosaicismNeocortexRecombination, GeneticSingle-Cell AnalysisCre recombinaseIntegrases3D reconstructionClonal analysisInterchromosomal recombinationLineage tracingMADMSerial sectioning

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.