Evidence map›Paper›PMID 39745612›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Capturing Chromatin Organization by MNase-seq and ATAC-seq.

Mika Saotome, Jill Goodman, Motoki Takaku

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mika SaotomeDepartment of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.
Jill GoodmanDepartment of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.
Motoki TakakuDepartment of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA. motoki.takaku@und.edu.

Funding

The role of class IIa Hdac in regulating cell fate choice in early cortical development.P20GM104360 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI ROCHE, BENJAMIN · 2013 to 2023
$21.1M
Role of nucleosome architecture in cellular reprogrammingR01GM148729 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI Motoki Takaku · 2023 to 2026
$1.4M
NIGMS NIH HHS P20 GM104360NIGMS NIH HHS R01 GM148729
6 · The paper itself

Abstract

Hox genes play a pivotal role during development. Their expression is tightly controlled in a spatiotemporal manner, ensuring that specific body structures develop at the correct locations and times during development. Various genomics approaches have been used to capture temporal and dynamic regulation of Hox gene expression at the nucleosome/chromatin level. This chapter focuses on the utilization of capture MNase-seq and Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq), two advanced techniques that enable the exploration of chromatin accessibility and nucleosome positioning within these critical genomic regions.

Indexed as

ChromatinNucleosomesAnimalsChromatin Assembly and DisassemblyChromatin Immunoprecipitation SequencingHigh-Throughput Nucleotide SequencingHumansMicrococcal NucleaseSequence Analysis, DNATransposasesChromatinMicrococcal NucleaseNucleosomesTransposasesATAC-seqChromatinEpigeneticsGene regulationMNase-seq

Identifiers

PMID39745612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.