Evidence map›Paper›PMID 39745603›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Tracking Abdominal-B Expression and Function in the Fly Internal Reproductive System by Explants Imaging.

David Foronda

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

David ForondaCentro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Madrid, Spain. dforonda@cbm.csic.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hox genes specify identities mainly in the anteroposterior axis in various animal tissues, some of them forming part of the internal organs and systems. The expression and activity of these genes have been analyzed mainly in Drosophila melanogaster, the fruit fly, and in mouse; in the former, the functional study of Hox genes has been detailed predominantly in epidermal structures, but their role in internal organs poses some challenges, particularly in pupae. One of these genes, Abdominal-B, dictates the development of many internal organs in the posterior abdomen of the fly, yet techniques for its analysis, like in vivo time-lapse, have long been impractical. The protocol outlined in this chapter presents a simple and effective method that not only addresses this issue but also opens up new approaches to previously inaccessible in vivo developmental questions, such as the spatial challenges of abdominal organ packing and the minimal requirements for the coordinated growth of organs.

Indexed as

Drosophila melanogasterDrosophila ProteinsAnimalsGene Expression Regulation, DevelopmentalGenitaliaHomeodomain ProteinsPupaAbd-B proteins, DrosophilaDrosophila ProteinsHomeodomain ProteinsAbdominal-AAbdominal-BCoilingElongationEx vivoImagingInternal genitaliaTestis

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.