Evidence map›Paper›PMID 39745541›Full record

ArticleAmerican journal of physiology. Renal physiology2025

Kir5.1 regulates Kir4.2 expression and is a key component of the 50-pS inwardly rectifying potassium channel in basolateral membrane of mouse proximal tubules.

Cheng-Biao Zhang, Zheng Ding, Xin-Peng Duan, Tanzina Chowdhury, Wen-Hui Wang, Dao-Hong Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mechanistic target of rapamycin complex-1 plays a role in inhibiting kidney KAmerican journal of physiology. Renal physiology · 2026
    Article
  2. Article
  3. KiScience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cheng-Biao ZhangDepartment of Physiology, Xuzhou Medical University, Xuzhou, People's Republic of China.
Zheng DingDepartment of Physiology, Xuzhou Medical University, Xuzhou, People's Republic of China.ORCID 0009-0002-8953-0931
Xin-Peng DuanDepartment of Physiology, Xuzhou Medical University, Xuzhou, People's Republic of China.
Tanzina ChowdhuryDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, New York, United States.
Wen-Hui WangDepartment of Pharmacology, New York Medical College, Valhalla, New York, United States.ORCID 0000-0002-7503-9554
Dao-Hong LinDepartment of Pharmacology, New York Medical College, Valhalla, New York, United States.ORCID 0000-0003-1760-2684

Funding

Role of Kir4.1 in regulating NCC and ROMK in DCTR01DK133220 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID HOADLEY, WANG, WENHUI · 2022 to 2025
$2.6M
Regulation of Kir4.1/Kir5.1 and renal potassium excretionR01DK136491 · NIDDK · NEW YORK MEDICAL COLLEGE · PI Dao-Hong Lin · 2023 to 2026
$1.4M
ZEISS LSM 980 plus AIRYSCAN 2 for NYMC Imaging CoreS10OD028527 · OD · NEW YORK MEDICAL COLLEGE · PI MORDUE, DANA G · 2020 to 2020
$594k
HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) RO1DK133220HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) RO1DK136491National Natural Science Foundation of China 31571187NIDDK NIH HHS R01 DK133220NIDDK NIH HHS R01 DK136491NIH HHS S10 OD028527NYMC Imaging Core shared instrumentation grant for an LSM 980 plus Airyscan 2
6 · The paper itself

Abstract

Kir5.1 encoded by

Indexed as

Cell MembraneKidney Tubules, ProximalKir5.1 ChannelPotassium Channels, Inwardly RectifyingAnimalsMaleMembrane PotentialsMiceMice, Inbred C57BLMice, KnockoutKcnj16 protein, mouseKir4.2 channelKir5.1 ChannelPotassium Channels, Inwardly RectifyingKcnj10Kcnj15Kcnj16potassium channelproximal tubule

Identifiers

PMID39745541
PMCPMC12207947

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.