Evidence map›Paper›PMID 39745530›Full record

ArticleAbdominal radiology (New York)2025

Exploring the potential of the combined diagnostic model of ADC value and bp-MRI VI-RADS in the evaluation of muscle invasion in bladder Cancer.

Zhichao Zhang, Weixiong Xiao, Yiqian Wang, Wei Zhang, Min Luo

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Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. What's next for VI-RADS? Updates and future perspectives from the ACR VI-RADS steering committee.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Review
  5. Article
  6. Article
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Zhichao ZhangDepartment of Radiology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Weixiong XiaoDepartment of Radiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China.
Yiqian WangDepartment of Radiology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Wei ZhangDepartment of Radiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China.
Min LuoDepartment of Radiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China. luomin6668@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigates the diagnostic value of Vesical Imaging Reporting and Data System (VI-RADS) in biparametric MRI (bp-MRI) for the detection of muscular infiltration in bladder cancer, and to investigate whether apparent diffusion coefficient (ADC) value can function as a potential indicator of bp-MRI VI-RADS for patient benefit. MATERIALS AND

methodsThis single-center retrospective study enrolled 81 patients with pathologically confirmed bladder cancer from October 2019 to November 2021. Two readers independently scored the T2-weighted images and diffusion-weighted images of each index lesion based on the VI-RADS criteria, subsequently deriving the bp-MRI VI-RADS scores. Both ADC values and bp-MRI VI-RADS scores were utilized to develop a simple model by logistic regression. Receiver-operating characteristic curve assessed all systems, while decision curve analysis (DCA) and calibration curves evaluated the model's performance.

resultsThe area under the curve (AUC) of bp-MRI VI-RADS was 0.886 (95% confidence interval [CI]: 0.801-0.971), with the diagnostic accuracy, sensitivity, and specificity being 0.753, 0.962, and 0.655 respectively. Regarding the ADC value, its AUC was 0.899 (95% CI: 0.821-0.977), and the diagnostic accuracy, sensitivity, and specificity were 0.877, 0.846, and 0.891. The AUC of the simple combined model achieved 0.942 (95% CI: 0.881-0.999), and the diagnostic accuracy, sensitivity, and specificity were 0.889, 0.885, and 0.891. The DeLong test verified that there was a statistically significant difference in AUC between the model and bp-MRI VI-RADS alone (P < 0.05). The simple model demonstrated excellent clinical applicability via DCA and calibration plots.

conclusionsThe contrast-free bp-MRI VI-RADS demonstrates commendable diagnostic efficacy for diagnosing muscular infiltration in bladder cancer. Additionally, ADC values can complement bp-MRI VI-RADS, enhancing diagnostic performance.

Indexed as

Diffusion Magnetic Resonance ImagingMagnetic Resonance ImagingMuscle NeoplasmsRadiology Information SystemsUrinary Bladder NeoplasmsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoplasm InvasivenessRetrospective StudiesSensitivity and SpecificityApparent diffusion coefficientBladder cancerMagnetic resonance imagingVesical imaging reporting and data system

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PMID39745530

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.